1-Naphthol
1-Naphthol Basic information
- Product Name:
- 1-Naphthol
- Synonyms:
-
- 1-naphthalenol
- 1-NAPHTHOL
- 1-naphtol
- α-Hydroxynaphthalene
- α-Maphthol
- 1-napthol(alpha-napthol)
- 1-naphthol (alpha)
- 1-Naphthol 97+ %
- CAS:
- 90-15-3
- MF:
- C10H8O
- MW:
- 144.17
- EINECS:
- 201-969-4
- Product Categories:
-
- Aromatics
- Functional Materials
- Chemistry
- Dyestuff Intermediates
- Bioactive Small Molecules
- Biochemicals and Reagents
- Building Blocks
- C9 to C20+
- Cell Biology
- Chemical Synthesis
- Detection
- Fluorescent Probes
- Labels
- N
- Intermediates of Dyes and Pigments
- Aromatic Compounds
- Color Former & Related Compounds
- Developer
- Organic Building Blocks
- Oxygen Compounds
- Particles and Stains
- Phenols
- Mol File:
- 90-15-3.mol
1-Naphthol Chemical Properties
- Melting point:
- 94-96 °C(lit.)
- Boiling point:
- 278-280 °C(lit.)
- Density
- 1.224
- vapor density
- 4.5 (120 °C, vs air)
- vapor pressure
- 1 mm Hg ( 94 °C)
- refractive index
- 1.6224
- Flash point:
- 125 °C
- storage temp.
- Store in dark!
- solubility
- Soluble in benzene, chloroform, ether and ethanol.
- pka
- 9.34(at 25℃)
- form
- Crystalline Flakes
- color
- white to off-white
- Odor
- Slight phenolic odor
- explosive limit
- 5%
- Water Solubility
- 436.7mg/L(25 ºC)
- λmax
- 324nm(MeOH)(lit.)
- Sensitive
- Air & Light Sensitive
- Merck
- 14,6383
- BRN
- 1817321
- Stability:
- Stable, but air and light sensitive - store under inert gas. Incompatible with strong bases, strong oxidizing agents.
- InChIKey
- KJCVRFUGPWSIIH-UHFFFAOYSA-N
- CAS DataBase Reference
- 90-15-3(CAS DataBase Reference)
- NIST Chemistry Reference
- 1-Naphthalenol(90-15-3)
- EPA Substance Registry System
- 1-Naphthol (90-15-3)
Safety Information
- Hazard Codes
- Xn,N
- Risk Statements
- 21/22-37/38-41-51/53
- Safety Statements
- 22-26-37/39-2-61
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 1
- RTECS
- QL2800000
- F
- 8-23
- Autoignition Temperature
- 510 °C
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29071510
- Hazardous Substances Data
- 90-15-3(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: 1870 mg/kg LD50 dermal Rabbit 880 mg/kg
MSDS
- Language:English Provider:Oxidation base 33
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
1-Naphthol Usage And Synthesis
Description
Alpha-naphtol, combined with epichlorhydrine and sodium hydroxide to form alpha-naphtyl glycidyl ether, caused sensitization in one of three workers in a chemical plant.
Chemical Properties
Pale grey to brown solid
Uses
Used in the manufacturing of dyes, intermediates, synthetic perfumes.
Definition
ChEBI: A naphthol carrying a hydroxy group at position 1.
Synthesis Reference(s)
Synthetic Communications, 21, p. 379, 1991 DOI: 10.1080/00397919108016759
Journal of the American Chemical Society, 107, p. 493, 1985 DOI: 10.1021/ja00288a037
Hazard
Toxic by ingestion and skin absorption.
Contact allergens
Alpha-naphthol can be used in dye manufacture and is classified as a hair dye. Combined with epichlorhydrin and NaOH to form alpha-naphthyl glycidyl ether, it caused sensitization in one of three workers in a chemical plant.
Safety Profile
Poison by ingestion and intraperitoneal routes. Moderately toxic by skin contact. An experimental teratogen. Experimental reproductive effects. A severe eye and skin irritant. Mutation data reported. Ingestion of large amounts can cause nephritis, vomiting, diarrhea, circulatory collapse, anemia, convulsions, and death. Can cause kidney irritation and injury to cornea and lens of the eye. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
Sublime 1-naphthol, then crystallise it from aqueous MeOH (charcoal), aqueous 25% or 50% EtOH, *C6H6, cyclohexane, heptane, CCl4 or H2O. Dry it over P2O5 in vacuo. The 4-nitrobenzoate has m 143o (from EtOH). [Shizuka et al. J Am Chem Soc 107 7816 1985, Beilstein 8 H 596, 6 IV 4208.]
1-Naphthol Preparation Products And Raw materials
Raw materials
Preparation Products
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1-Naphthol(90-15-3)Related Product Information
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- ALPHA-NAPHTHOLBENZEIN
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