2-Chloro-N,N-diethylacetamide Chemical Properties

Melting point:

58 °C

Boiling point:

121-122 °C (12 mmHg)

Density 

1.089 g/mL at 25 °C(lit.)

refractive index 

1.469-1.471

Flash point:

>110°C

storage temp. 

Store below +30°C.

solubility 

85.5g/l

form 

Liquid or Solid

pka

-0.95±0.70(Predicted)

Specific Gravity

1.089

color 

Clear colorless to light yellow

Water Solubility 

soluble

BRN 

605866

InChIKey

CQQUWTMMFMJEFE-UHFFFAOYSA-N

CAS DataBase Reference

2315-36-8(CAS DataBase Reference)

NIST Chemistry Reference

Acetamide, 2-chloro-N,N-diethyl-(2315-36-8)

EPA Substance Registry System

Acetamide, 2-chloro-N,N-diethyl- (2315-36-8)

Safety Information

Hazard Codes 

T+,Xn,Xi,F

Risk Statements 

36/37/38-26-21/22-20/21/22-38-11

Safety Statements 

45-38-36/37/39-28A-26-28-36-16

RIDADR 

2810

WGK Germany 

3

RTECS 

AB5425000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29241900

Toxicity

LD50 orally in Rabbit: 500 mg/kg LD50 dermal Rat 980 mg/kg

MSDS

• Language:English Provider:2-Chloro-N,N-diethylacetamide
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chloro-N,N-diethylacetamide Usage And Synthesis

Chemical Properties

clear brown liquid

Uses

2-Chloro-N,N-diethylacetamide has been used in:

• preparation of calixarene amides
• synthesis of 5-bromo-25,26,27,28-tetrakis[(N,N-diethylaminocarbonyl)-methoxy]calix[4]arene
• synthesis of amide calix[4]pyrrole macrocycles with super-extended cavities
• microwave-assisted organic synthesis of 3-cyano-N,N-diethyl-4-(4-methoxyphenoyl)-4-oxobutanamide

Application

2-Chloro-N,N-diethylacetamide is mainly used in the synthesis of amides.

2-Chloro-N,N-diethylacetamide(2315-36-8)Related Product Information

• 2,2,2-Trichloroacetamide
• Chloroacetamide
• N,N-Dimethylacetamide
• 2-Cyano-N,N-diethylacetamide
• Acetamide
• Dichloroacetamide
• Phenethyl chloride
• DIACETAMIDE
• DIETHYLALUMINUM CHLORIDE
• N,N-DIETHYL-2-PHENYLACETAMIDE
• N,N-diethyl-4-forMylbenzaMide
• Difluorochloromethane
• 2-Chloro-N,N-bis(2-methylpropyl)acetamide
• Dichlormid
• ALLIDOCHLOR
• PHOSPHAMIDON
• a,a-Dichloro-N,N-Diethylacetylacetamide
• Diethylacetamide