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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyridazine compounds >  3,6-Dihydroxy-4,5-dimethylpyridazine

3,6-Dihydroxy-4,5-dimethylpyridazine

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3,6-Dihydroxy-4,5-dimethylpyridazine Basic information

Product Name:
3,6-Dihydroxy-4,5-dimethylpyridazine
Synonyms:
  • 3,6-Dihydroxy-4,5-dimethylpyridazine
  • 3,6-DIHYDROXY-4,5-DIMETHYLPYRIDAZINE (4,5-DIMETHYLMALEIC HYDRAZIDE)
  • 4,5-Dimethylpyridazine-3,6-diol
  • 4,5-dimethyl-1,2-dihydropyridazine-3,6-dione
  • 4,5-dimethyl-1,2-dihydropyridazine-3,6-quinone
  • 1,2-Dihydro-4,5-dimethyl-3,6-pyridazinedione
  • Dimethylmaleic acid dimethyl cyclic hydrazide
  • diMethylpyridazine-3,6-diol
CAS:
5754-17-6
MF:
C6H8N2O2
MW:
140.14
EINECS:
1312995-182-4
Product Categories:
  • Pyridazine series
Mol File:
5754-17-6.mol
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3,6-Dihydroxy-4,5-dimethylpyridazine Chemical Properties

Melting point:
347-351 °C
Density 
1.160±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
9.08±0.60(Predicted)
CAS DataBase Reference
5754-17-6
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Safety Information

Hazard Codes 
T
Hazard Note 
Toxic
HS Code 
2933998090
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3,6-Dihydroxy-4,5-dimethylpyridazine Usage And Synthesis

Uses

4,5-Dimethylpyridazine-3,6-diol is a useful research chemical.

Uses

3,6-Dihydroxy-4,5-dimethylpyridazine can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis


Hydrazine hydrochloride (58 g, 552 mmol) is dissolved in hot water (300 mL) and dimethyl maleic anhydride (58 g, 460 mmol) is added in portions and the suspension stirred at reflux for 16 h. The suspension is cooled down to room temperature and the precipitate is filtered, washed with water and dried at 40° C. under vacuum to yield 4,5-dimethyl-1,2-dihydro-pyridazine-3,6-dione (36) (64 g, 99%).

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