8-AMINOGUANOSINE Chemical Properties

Melting point:

261°C dec.

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

Aqueous Acid (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)

form 

powder

color 

white to brown

CAS DataBase Reference

3868-32-4(CAS DataBase Reference)

Safety Information

HS Code 

29389090

8-AMINOGUANOSINE Usage And Synthesis

Chemical Properties

Off-White to Tan Solid

Uses

A potent inhibitor of purine nucleoside phosphorylase

Biological Activity

8-Aminoguanosine, a guanosine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic th at increased sodium excretion by 26.2-fold and decrease potassium excretion by 69.1%. 8-Aminoguanosine increases glucose excretion by 12.2-fold. Also 8-Aminoguanosine suppressed deoxycorticosterone/salt-induced hypertension.', '8-Aminoguanosine is known to stimulate diuresis, natriuresis, glucosuria and antikaliuresis. It is an analog of guanosine, th at can block purine nucleoside phosphorylase, in vitro and in intact lymphoid cells. 8-aminoguanosine triphosphate can be used to block GTP (guanosine triphosphate) cyclohydrolase I from human liver and Escherichia coli.

8-AMINOGUANOSINE(3868-32-4)Related Product Information

• Gelatin
• DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
• 8-aminoguanosine triphosphate
• N(7)-aminoguanosine
• 2''-AMINO-2''-DEOXYGUANOSINE (2''-DEOXY-2''-AMINOGUANOSINE)
• N1-AMINOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT,n1-aminoguanosine-3’,5’-cyclicmonophosphate(1-nh2-cgmp),sodiumsal
• 8-METHYLAMINOGUANOSINE
• 8-AZIDOGUANOSINE 5'-TRIPHOSPHATE
• 8-Nitro-D-guanosine
• 8-AMINOGUANOSINE
• 8-AZIDO CGMP 32P TRIETHYLAMMONIUM SALT
• 8-AZIDO GTP ALPHA-32P TRIETHYLAMMONIUM SALT