ROS Chemical Properties

storage temp. 

-20°C

form 

buffered aqueous glycerol solution

Specific Activity

544-736nmol/min·mg

Safety Information

WGK Germany 

WGK 1

Storage Class

10 - Combustible liquids

ROS Usage And Synthesis

Uses

ROS1 is a proto-oncogene and member of the sevenless subfamily of tyrosine kinase insulin receptor genes. ROS1 is highly-expressed in a variety of tumor cell lines and functions as a growth or differentiation factor receptor. The FIG gene can fuse with the ROS1 gene in glioblastoma cell lines. The resulting ROS1/FIG fusion protein is a constitutively activated tyrosine kinase. Direct interaction of ROS1 and the phosphatase SHP-1 can lead to efficient downregulation of ROS1-mediated signaling. Binding sites in the ROS1 cytoplasmic domain display high affinity binding to the SHP-1 N-terminal SH2 domain.

ROS()Related Product Information

• Tissue Reactive Oxygen Species (ROS) Detection Kit
• DNMT1-mouse
• HDAC6
• MOLGRASTIM
• Human FGF-21
• sortase
• PARP
• HUMAN IL-13
• Mouse Anti-SAA1 antibody
• Protein-L Cys