Basic information Safety Supplier Related

PROTOVERATRINE A+B

Basic information Safety Supplier Related

PROTOVERATRINE A+B Basic information

Product Name:
PROTOVERATRINE A+B
Synonyms:
  • PROTOVERATRINE A AND B
  • PROTOVERATRINE A+B
  • PROTOVERATRINE
MF:
C82H126N2O29
MW:
1603.87
Mol File:
Mol File
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PROTOVERATRINE A+B Chemical Properties

Melting point:
275-283°C
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PROTOVERATRINE A+B Usage And Synthesis

Description

An alkaloid of Veratrum album, this base was first isolated by Salzberger and reexamined by Poethke. The above formula is due to Jacobs and Craig who also describe the melting point as varying with the rate of heating. It has [α]27D - 40° (pyridine) or - 9.1 ° (CHC13). The alkaloid dissolves in H2S04 giving a blue colour that changes to violet on heating. In HCl and H3P04, the colour is cherryred. The hydrochloride monohydrate forms small tablets, m.p. 234-6°C (dry, dec.); the hydro bromide trlhydrate melts at 230-2°C (dec.); the aurichloride, m.p. 199°C (dec.) and the picrate, m.p. 216-220°C (dec.). On alkaline hydrolysis the alkaloid yields protoverine, acetic, methylethylacetic and methylethylglycollic acids.

Uses

Medicine to lower blood pressure.

Definition

A substance isolated from the Veratrum album plant. It is a mixture of two alka- loids, designated protoveratrine A and protovera- trine B.

brand name

Protalba (Marion Merrell Dow).

References

Salzberger., Arch. Pharm., 228,462 (1890)
Poethke., ibid, 275,571 (1937)
Jacobs, Craig.,!. Bioi. Chem., 143, 427 (1942)
Jacobs, Craig., ibid, 149,271 (1943)

PROTOVERATRINE A+BSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
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PROTOVERATRINE A+B()Related Product Information