ANTI-AMPHOTERIN Chemical Properties

storage temp. 

-20°C

form 

buffered aqueous solution

biological source

rabbit

Safety Information

Hazard Codes 

Xi

Risk Statements 

36-52/53

Safety Statements 

26-61

WGK Germany 

-

Storage Class

12 - Non Combustible Liquids

MSDS

• Language:English Provider:SigmaAldrich

ANTI-AMPHOTERIN Usage And Synthesis

Uses

This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Biological Activity

HMGB1 belongs to the HMGB family. It contains 2 HMG box DNA-binding domains. The protein binds preferentially single-stranded DNA and unwinds double stranded DNA. The oxidized HMGB1 may accumulate even in cells under oxidative stress.

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