5-FORMYLURACIL Chemical Properties

Melting point:

>300 °C (dec.) (lit.)

Density 

1.567±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

7.27±0.10(Predicted)

form 

Solid

color 

White to Pale Yellow

Sensitive 

Air Sensitive

InChIKey

OHAMXGZMZZWRCA-UHFFFAOYSA-N

CAS DataBase Reference

1195-08-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

5-FORMYLURACIL Usage And Synthesis

Chemical Properties

White Powder

Uses

Nucleoside derivatives of 5-substituted uracil have been explored for their potential application as anti-viral agents and in the treatment of tumors.

Uses

5-Formyluracil may be used for the preparation of covalently linked base with 5-aminocytosine pair via Schiff base formation.

Definition

ChEBI: A pyrimidone resulting from the formal oxidation of the alcoholic hydroxy group of 5-hydroxymethyluracil to the corresponding aldehyde. It is a major one-electron photooxidation product of thymine in oligodeoxynucleotides.

Synthesis Reference(s)

Tetrahedron Letters, 7, p. 5253, 1966 DOI: 10.1016/0005-2760(66)90119-6

5-FORMYLURACIL(1195-08-0)Related Product Information

• 5-ACETYLURACIL
• 5-CARBETHOXYURACIL
• 1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE
• 2,4-Dihydroxypyrimidine-5-carboxylic acid
• 4-FORMYLURACIL MONOHYDRATE,6-FORMYLURACIL MONOHYDATE
• Uracil
• 6-AMINO-1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBALDEHYDE
• 5-ACETYL-1-[(4-CHLOROBENZYL)OXY]-2,4(1H,3H)-PYRIMIDINEDIONE
• 5-ACETYL-1-METHOXY-2,4(1H,3H)-PYRIMIDINEDIONE
• ETHYL N-[(1-MORPHOLINO-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINYL)CARBONYL]CARBAMATE
• 5-ACETYL-3-(4-BROMOBENZYL)-1-(4-CHLOROPHENYL)-2,4(1H,3H)-PYRIMIDINEDIONE
• 5-ACETYL-1-(4-CHLOROPHENYL)-2,4(1H,3H)-PYRIMIDINEDIONE
• 5-ACETYL-1-(4-METHYLPIPERAZINO)-2,4(1H,3H)-PYRIMIDINEDIONE
• 5-ACETYL-1-(2-HYDROXY-ETHYL)-1H-PYRIMIDINE-2,4-DIONE
• 5-ACETYL-1-PIPERIDINO-2,4(1H,3H)-PYRIMIDINEDIONE
• ETHYL N-[(1-METHOXY-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINYL)CARBONYL]CARBAMATE
• ETHYL N-([1-(4-METHOXYPHENYL)-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINYL]CARBONYL)CARBAMATE
• ETHYL N-((1-[(4-CHLOROBENZYL)OXY]-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINYL)CARBONYL)CARBAMATE