Dideoxyadenosine
Dideoxyadenosine Basic information
- Product Name:
- Dideoxyadenosine
- Synonyms:
-
- [(2S,5R)-5-(6-Aminopurin-9-yl)oxolan-2-yl]methanol
- NSC 98700
- Didanosine Related CoMpound B
- 2',3'-DIDEOXYADENOSINE extapure
- 2’,3’-dideoxy-adenosin
- 2',3'-Dideoxy-D-adenosine
- 9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine
- Didanosine Impurity 7（Didanosine EP Impurity G）
- CAS:
- 4097-22-7
- MF:
- C10H13N5O2
- MW:
- 235.24
- EINECS:
- 223-853-2
- Product Categories:
-
- Carbohydrates & Derivatives
- Heterocycles
- Intermediates & Fine Chemicals
- Nucleotides
- Pharmaceuticals
- Isotope Labelled Compounds
- Antivirals for Research and Experimental Use
- Biochemistry
- Chemical Reagents for Pharmacology Research
- Nucleosides and their analogs
- Nucleosides, Nucleotides & Related Reagents
- Bases & Related Reagents
- Nucleosides-Dideoxy Nucleosides
- Mol File:
- 4097-22-7.mol
Dideoxyadenosine Chemical Properties
- Melting point:
- 181-184 °C(lit.)
- alpha
- D25 -25.2° (c = 1.01 in water)
- Boiling point:
- 377.64°C (rough estimate)
- Density
- 1.2455 (rough estimate)
- refractive index
- -34 ° (C=1, H2O)
- storage temp.
- -20°C
- solubility
- DMF: 1 mg/mL; DMSO: 2 mg/mL; Ethanol: Slightly soluble
- pka
- pKa 3.84(H2O t=25.0±0. I=0.01) (Uncertain)
- form
- Powder
- color
- White to Off-white
- Water Solubility
- 43.2g/L(25 ºC)
- Merck
- 14,3101
- BRN
- 619924
- InChIKey
- WVXRAFOPTSTNLL-NKWVEPMBSA-N
- CAS DataBase Reference
- 4097-22-7(CAS DataBase Reference)
- EPA Substance Registry System
- Adenosine, 2',3'-dideoxy- (4097-22-7)
Safety Information
- Hazard Codes
- C
- Risk Statements
- 34-36/37-22
- Safety Statements
- 26-27-36/37/39-45-24/25
- WGK Germany
- 2
- RTECS
- AU7358900
- HS Code
- 29349990
- Toxicity
- LD50 oral in mouse: 5gm/kg
MSDS
- Language:English Provider:2',3'-Dideoxy-adenosine
- Language:English Provider:SigmaAldrich
Dideoxyadenosine Usage And Synthesis
Chemical Properties
Beige power
Uses
Dideoxy Adenosine (Didanosine EP Impurity G) is a potent anti-HIV agent.
Uses
2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation.
Uses
A potent labelled anti-HIV agent.
Uses
A potent anti-HIV agent.
Definition
ChEBI: A purine 2',3'-dideoxyribonucleoside in which the nucleobase component is specified as adenine.
General Description
Off-white powder.
Air & Water Reactions
Water soluble.
Reactivity Profile
Dideoxyadenosine may be sensitive to prolonged exposure to light.
Health Hazard
SYMPTOMS: Symptoms of exposure to a related compound include cutaneous eruptions, fever, mouth sores, thrombocytopenia, neutropenia, reversible peripheral neuropathy, gastrointestinal distress, headache, nausea and vomiting.
Fire Hazard
Flash point data for Dideoxyadenosine are not available; however, Dideoxyadenosine is probably combustible.
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Dideoxyadenosine(4097-22-7)Related Product Information
- 2',3'-Dideoxyguanosine
- 2',3'-Dideoxythymidine
- EC 3.5.4.4
- 5'-Deoxyadenosylcobalamin
- 2'-Deoxyadenosine
- Adenosine
- Cyclic AMP
- Vidarabine
- ADENOSINE 5'-TRIPHOSPHATASE
- Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI)
- 2'-Deoxyadenosine monohydrate
- 2'-Deoxyadenosine 5'-phosphate
- DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
- 8-BROMOADENOSINE
- 5'-Tosyladenosine
- Adenosine 5'-monophosphate monohydrate
- 2-Chloroadenosine
- N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine