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5-Methoxy cytidine

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5-Methoxy cytidine Basic information

Product Name:
5-Methoxy cytidine
Synonyms:
  • 5-Methoxy cytidine
  • 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxypyrimidin-2-one
  • Cytidine, 5-methoxy-
  • 5-OMe-Cr
  • 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidin-2(1H)-one
CAS:
37805-90-6
MF:
C10H15N3O6
MW:
273.24
Mol File:
37805-90-6.mol
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5-Methoxy cytidine Chemical Properties

Boiling point:
569.9±60.0 °C(Predicted)
Density 
1.81±0.1 g/cm3(Predicted)
pka
13.48±0.70(Predicted)
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5-Methoxy cytidine Usage And Synthesis

Uses

5-Methoxy cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

References

[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308

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