2-Morpholinoethanol Chemical Properties

Melting point:

-1 °C

Boiling point:

227 °C757 mm Hg(lit.)

Density 

1.083 g/mL at 25 °C(lit.)

vapor pressure 

2.44-7Pa at 20-25℃

refractive index 

n20/D 1.476(lit.)

Flash point:

211 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Liquid

pka

14.88±0.10(Predicted)

color 

Clear colorless to yellow

PH

10.7 (100g/l, H2O, 20℃)

explosive limit

1.5-9.8%(V)

Water Solubility 

miscible

BRN 

104375

LogP

-1.32 at 25℃

CAS DataBase Reference

622-40-2(CAS DataBase Reference)

NIST Chemistry Reference

4-Morpholineethanol(622-40-2)

EPA Substance Registry System

4-Morpholineethanol (622-40-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

1

RTECS 

QE3510000

F 

10-23

TSCA 

Yes

HS Code 

29349990

MSDS

• Language:English Provider:2-Morpholinoethanol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Morpholinoethanol Usage And Synthesis

Chemical Properties

2-Morpholinoethanol is a transparent colorless to yellow liquid. It is used as an organic chemical synthesis intermediate.

Uses

4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary cu lture/DNA.

Definition

ChEBI: 2-Morpholinoethanol is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group. It is a primary alcohol, a tertiary amino compound and a member of morpholines.

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 467, 1987 DOI: 10.1021/jo00379a035

Flammability and Explosibility

Non flammable

2-Morpholinoethanol(622-40-2)Related Product Information

• Moroxydine
• Hydroxyethyl starch
• Tridemorph
• Dimethomorph
• Hydroxyethyl Cellulose
• Sodium isethionate
• Moroxydine hydrochloride
• N-Formylmorpholine
• 2-(METHYLSULFONYL)ETHANOL
• 2-(2-Aminoethylamino)ethanol
• Methyl 2-hydroxyethyl cellulose
• Ethanol
• 2-Piperidinoethanol
• morpholine
• 3-MORPHOLINO-1,2-PROPANEDIOL
• 4-(2,3-EPOXYPROPYL)MORPHOLINE
• ETHYL MORPHOLINOACETATE, 98
• MOPSO