Basic information Safety Supplier Related

Lipoamido-PEG3-alcohol

Basic information Safety Supplier Related

Lipoamido-PEG3-alcohol Basic information

Product Name:
Lipoamido-PEG3-alcohol
Synonyms:
  • Lipoamido-PEG3-alcohol
  • LA-PEG3-OH
  • LIPOAMIDO-PEG3-OH
  • 1,2-Dithiolane-3-pentanamide, N-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]-
CAS:
1342764-64-0
MF:
C16H31NO5S2
MW:
381.55
Product Categories:
  • peg
Mol File:
1342764-64-0.mol
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Lipoamido-PEG3-alcohol Chemical Properties

Boiling point:
573.8±40.0 °C(Predicted)
Density 
1.158±0.06 g/cm3(Predicted)
pka
14.36±0.10(Predicted)
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Lipoamido-PEG3-alcohol Usage And Synthesis

Description

Lipoamido-PEG3-alcohol has lipoamide and hydroxyl end groups. The hydroxyl group can undergo reactions to further derivatize the compoud. The hydrophilic PEG chain increases the water solubility of the compound in aqueous environments.

Uses

Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform[1].

IC 50

PEGs

References

[1] Saha Ray A,et al. Set of Highly Stable Amine- and Carboxylate-Terminated Dendronized Au Nanoparticles with Dense Coating and Nontoxic Mixed-Dendronized Form.Langmuir. 2019 Mar 5;35(9):3391-3403. DOI:10.1021/acs.langmuir.8b03196

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