Basic information Safety Supplier Related

Propargyl-PEG8-alcohol

Basic information Safety Supplier Related

Propargyl-PEG8-alcohol Basic information

Product Name:
Propargyl-PEG8-alcohol
Synonyms:
  • Propargyl-PEG8-alcohol
  • Alkyne-PEG7-OH
  • Propargyl-PEG7-OH
  • 3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol
  • Propargyl-PEG7-OH/3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol
  • 2-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • HO-PEG7-Propargyl
CAS:
1422023-54-8
MF:
C17H32O8
MW:
364.43
Product Categories:
  • peg
Mol File:
1422023-54-8.mol
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Propargyl-PEG8-alcohol Chemical Properties

storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
Liquid
color 
Colorless to light yellow
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Propargyl-PEG8-alcohol Usage And Synthesis

Description

Propargyl-PEG8-alcohol has a hydroxyl group and a propargyl group. The propargyl group can participate in copper catalyzed azide-alkyne Click Chemistry.

Uses

Propargyl-PEG7-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG7-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26. DOI:10.1039/c2ob26968f

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