Propargyl-PEG8-alcohol
Propargyl-PEG8-alcohol Basic information
- Product Name:
- Propargyl-PEG8-alcohol
- Synonyms:
-
- Propargyl-PEG8-alcohol
- Alkyne-PEG7-OH
- Propargyl-PEG7-OH
- 3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol
- Propargyl-PEG7-OH/3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol
- 2-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
- HO-PEG7-Propargyl
- CAS:
- 1422023-54-8
- MF:
- C17H32O8
- MW:
- 364.43
- Product Categories:
-
- peg
- Mol File:
- 1422023-54-8.mol
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Propargyl-PEG8-alcohol Chemical Properties
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
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Propargyl-PEG8-alcohol Usage And Synthesis
Description
Propargyl-PEG8-alcohol has a hydroxyl group and a propargyl group. The propargyl group can participate in copper catalyzed azide-alkyne Click Chemistry.
Uses
Propargyl-PEG7-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG7-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26. DOI:10.1039/c2ob26968f
Propargyl-PEG8-alcoholSupplier
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Propargyl-PEG8-alcohol(1422023-54-8)Related Product Information
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- Propargyl-PEG17-acid
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- Propargyl-PEG15-t-butyl ester
- Propargyl-PEG9-t-butyl ester
- Propargyl-PEG7-alcohol
- Propargyl-PEG6-acid
- Propargyl-PEG15-acid
- Propargyl-PEG8-t-butyl ester
- Propargyl-PEG9-alcohol
- Propargyl-PEG6-Tos