THP-SS-PEG1-t-butyl ester
THP-SS-PEG1-t-butyl ester Basic information
- Product Name:
- THP-SS-PEG1-t-butyl ester
- Synonyms:
-
- THP-SS-PEG1-t-butyl ester
- THP-SS-PEG1-Boc
- Propanoic acid, 3-[2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester
- THP-SS-PEG1-t-butyl ester THP-
- tert-Butyl 3-(2-((2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)disulfaneyl)ethoxy)propanoate
- tert-Butyl 3-[2-[[2-[(Tetrahydro-2H-pyran-2-yl)oxy]ethyl]disulfanyl]ethoxy]propanoate
- CAS:
- 1807503-88-3
- MF:
- C16H30O5S2
- MW:
- 366.54
- Mol File:
- 1807503-88-3.mol
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THP-SS-PEG1-t-butyl ester Chemical Properties
- Boiling point:
- 470.0±45.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
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THP-SS-PEG1-t-butyl ester Usage And Synthesis
Uses
THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50
Disulfide Cleavable Linker; Cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
THP-SS-PEG1-t-butyl esterSupplier
Bide Pharmatech Ltd.
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TargetMol Chemicals Inc.
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