tianeptine sulfate Chemical Properties

InChI

InChI=1S/2C21H25ClN2O4S.H2O4S.2H2O/c2*1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28;1-5(2,3)4;;/h2*5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26);(H2,1,2,3,4);2*1H2

InChIKey

KVVMXNNJBVTOSX-UHFFFAOYSA-N

SMILES

ClC1C([H])=C([H])C2=C(C=1[H])S(N(C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])(=O)=O.ClC1C([H])=C([H])C2=C(C=1[H])S(N(C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])(=O)=O.S(=O)(=O)(O[H])O[H].O([H])[H].O([H])[H]

tianeptine sulfate Usage And Synthesis

Physical properties

Tianeptine sulfate is more stable than tianeptine sodium which is notoriously unstable; it reacts to both atmospheric moisture and to light. Tianeptine sulfate on the other hand does not absorb the water from air so it does not clump.Tianeptine sulfate is soluble and cam be mixed easily with water.

Uses

Tianeptine sulfate is classified as a selective serotonin reuptake enhancer (SSRE) used to treat depression. Tianeptine was developed in France in the 1960s and has been used throughout the last part of the 2000s. Tianeptine sulfate improves brain neuroplasticity and decreases depression. Neuroplasticity is the brain’s ability to adapt and change when learning; contributing to better cognitive performance and improved learning ability.

Definition

Tianeptine is used as a prescription drug in some European, Asian, and Latin American countries, but it is not approved as a drug in the United States. The FDA is aware of several serious adverse event reports associated with tianeptine. Tianeptine is also known as: Tianeptine sulfate, Tianeptine sodium powder, Tianaa, Tianna Green, Tianna Red, and Tianna White.

Pharmacokinetics

The effect tianeptine sulfate lasts longer than tianeptine sodium. Tianeptine sulfate is absorbed by the body slowly so its effect is also extended and that means less dosing.

Side effects

Tianeptine is prescribed as an antidepresant in Europe. The prescription drug is produced as tianeptine sodium. The most common adverse effects of Tianeptine are nausea, constipation, abdominal pain, headache, dizziness and changes in dreaming. Anticholinergic effects occur less often with tianeptine than with tricyclic agents. Hepatoxicity is rare.

tianeptine sulfate(1224690-84-9)Related Product Information

• Tianeptine sodium salt
• Tianeptine Ethyl Ester
• Tianeptine