dibenzo[b,d]furan-3-ylboronic acid Chemical Properties

Boiling point:

438.5±37.0 °C(Predicted)

Density 

1.34±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

8.20±0.30(Predicted)

Safety Information

HS Code 

2931900090

dibenzo[b,d]furan-3-ylboronic acid Usage And Synthesis

Uses

Dibenzo[b,d]furan-3-ylboronic acid can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical and pharmaceutical production processes.

Synthesis

In a 300 ml three-necked flask, 7.2 g of 4-bromodibenzofuran was dissolved in ?78° C. anhydrous tetrahydrofuran (THF) under an argon atmosphere. Then, 20 ml of an n-butyl lithium-n-hexane solution (1.6 M, 1.1 eq) was added and stirred for 1 hour. 4.23 ml (1.3 eq) of trimethoxyborane (B(OMe)3) was added and stirred for 2 hours, and the temperature of the reaction system was increased to room temperature. 200 ml of 1 N hydrochloric acid was added into the reactant and stirred for 3 hours. An organic layer was separated, and solvents were distilled off. In the crude product thus obtained, hexane was added. Precipitated product was filtered to obtain 4.94 g of dibenzofuran-4-boronic acid as a white solid (yield 80percent). The product was measured by FAB-MS, and dibenzofuran-4-boronic acid having a molecular weight of 212 was detected.

dibenzo[b,d]furan-3-ylboronic acid(395087-89-5)Related Product Information

• dibenzo[b,d]thiophene-4-carbaldehyde
• Dibenzofuran -4,6 -diborate
• Dibenzothiophene-2-carboxaldehyde
• Dibenzothiophene-2-boronic acid
• 1-Dibenzofuranylboronic Acid
• 2-(Dibenzo[b,d]furan-1-yl)-4,4,5,5,-tetramethyl-1,3,2-dioxaborolane
• Dibenzothiophene
• DIBENZOFURAN-4-CARBOXALDEHYDE 97
• DIBENZOFURAN-4-BORONIC ACID
• Dibenzo[b,d]furan-2-ylboronic acid
• DIBENZOFURAN-2-CARBOXALDEHYDE