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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-

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1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Basic information

Product Name:
1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-
Synonyms:
  • Palonosetron Impurity 2
  • 2-[(3S)-1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one
  • Palonosetron USP RC B
  • Palonosetron USP Related Compound B
  • (S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine1-oxide
  • Palonosetron USP Related Compound B HCl
  • Dehydro palonosetron N-oxide
  • Palonosetron Related Compound B (Palonosetron-3-ene N-Oxide)
CAS:
1021456-82-5
MF:
C19H22N2O2
MW:
310.39
Mol File:
1021456-82-5.mol
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1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Chemical Properties

solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
pka
4.72±0.40(Predicted)
color 
Off-White to Pale Yellow
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Safety Information

HS Code 
2933790002
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1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Usage And Synthesis

Uses

Palonosetron-3-ene N-Oxide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

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