ChemicalBook > Product Catalog > Catalyst and Auxiliary > polymer > 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Basic information
- Product Name:
- 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
- Synonyms:
-
- 4-[2-[2-[2-[2-(4-aminophenoxy)ethoxy]ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
- Cereblon Ligand-Linker Conjugates 9
- 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
- E3 Ligase Ligand-Linker Conjugates 2
- 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-[2-[2-(4-aminophenoxy)ethoxy]ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-
- Cereblon Ligand-Linker Conjugates 9(E3 Ligase Ligand-Linker Conjugates 2)
- 4-[[2-[2-[2-[2-(4-Aminophenoxy)ethoxy]ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
- 4-[12-(4-aminophenoxy)-4,7,10-trioxa-1-azadodecan-1-yl]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
- CAS:
- 1818885-63-0
- MF:
- C27H32N4O8
- MW:
- 540.57
- Product Categories:
-
- peg
- Mol File:
- 1818885-63-0.mol
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4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Chemical Properties
- Boiling point:
- 792.0±60.0 °C(Predicted)
- Density
- 1.363±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 10.74±0.40(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Usage And Synthesis
Description
Pomalidomide-PEG4-Ph-NH2 is comprised of the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. Pomalidomide-PEG4-Ph-NH2 is used in PROTAC technology as a E3 ligase ligand-linker conjugate that incorporates PEG technology that can be linked to a wide range of "warheads" that bind to proteins of interest.
4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneSupplier
Shanghai Topbiochem Technology Co., Ltd
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Shanghai XinKai Chemical Technology Co., Ltd.
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Shanghai SuperLan Chemcial Technique Centre
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4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione(1818885-63-0)Related Product Information
- E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate
- E3 ligase Ligand-Linker Conjugates 5 Free Base
- Thalidomide-O-amido-C3-NH2 (TFA)
- N-(4-aminobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide TFA salt
- E3 ligase Ligand-Linker Conjugates 17
- E3 ligase Ligand-Linker Conjugates 14