Basic information Safety Supplier Related

FGF-401

Basic information Safety Supplier Related

FGF-401 Basic information

Product Name:
FGF-401
Synonyms:
  • N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
  • N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
  • Roblitinib(FGF-401)
  • FGF 401;FGF-401
  • 8-naphthyridine-1(2H)-carboxamide
  • 0997
  • N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide
  • Roblitinib
CAS:
1708971-55-4
MF:
C25H30N8O4
MW:
506.56
Product Categories:
  • API
Mol File:
1708971-55-4.mol
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FGF-401 Chemical Properties

Boiling point:
852.1±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
pka
11.40±0.20(Predicted)
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FGF-401 Usage And Synthesis

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

FGF-401Supplier

Shanghai Synchem Pharma Co., ltd Gold
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Shanghai Dongyang Biotechnology Co., Ltd. Gold
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13601744364
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chemsharker@126.com
Kaixin Chemical (Hong Kong) Limited Gold
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010-88886666-01 13112345678
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loyson@tcypharm.com
Shanghai Boyle Chemical Co., Ltd.
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sales@boylechem.com
Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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isenchem@163.com