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SARALASIN

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SARALASIN Basic information

Product Name:
SARALASIN
Synonyms:
  • (Sar1,Val5,Ala8)-Angiotensin II Saralasin
  • [Sar1, Val5, Ala8]-Angiotensin II acetate salt hydrate
  • SAR-ARG-VAL-TYR-VAL-HIS-PRO-ALA-OH
  • SAR-ARG-VAL-TYR-VAL-HIS-PRO-ALA
  • [SAR1,VAL5, ALA8]ANGIOTENSIN II, HUMAN
  • (SAR1,VAL5,ALA8)-ANGIOTENSIN II
  • SARALASIN
  • [sar1, val5, ala8]-angiotensin ii acetate hydrate
CAS:
34273-10-4
MF:
C42H65N13O10
MW:
912.05
Product Categories:
  • Angiotensin
Mol File:
34273-10-4.mol
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SARALASIN Chemical Properties

Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
powder
pka
3.70±0.10(Predicted)
Sequence
{Sar}-Arg-Val-Tyr-Val-His-Pro-Ala
CAS DataBase Reference
34273-10-4
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Safety Information

WGK Germany 
3
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SARALASIN Usage And Synthesis

Uses

Antihypertensive.

Uses

Saralasin are angiotensin II receptor agonists.

Definition

ChEBI: Saralasin is an oligopeptide.

brand name

Sarenin (Procter & Gamble).

in vivo

Saralasin (intravenous injection, 5-50 μg/kg, a single dose) ameliorates the oxidative stress and tissue injury in cerulein-induced pancreatitis[5].
Saralasin (subcutaneous injection, 10 and 30 mg/kg, a single dose) increases serum renin activity (SRA) in normal, conscious rats, without markedly altering blood pressure or heart rate[6].

Animal Model:Cerulein-induced acute pancreatitis rats model[5]
Dosage:5, 10, 20, and 50 μg/kg, a single dose.
Administration:Intravenous injection
Result:Restored the pancreatic morphological characteristics to the control level.
Reduced pancreatic injury and suppressed the glutathione depletion induced by cerulean.
Animal Model:Male Sprague-Dawley rats[6]
Dosage:10 and 30 mg/kg, a single dose.
Administration:Subcutaneous injection
Result:Stimulated renin release without altering blood pressure or heart rate at the time of measuring serum renin levels 20 minutes after injection.

SARALASINSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Email
ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Email
info@cellmano.com
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