2-Chloro-5-nitrobenzoic acid Chemical Properties

Melting point:

165-168 °C (lit.)

Boiling point:

356.5±27.0 °C(Predicted)

Density 

1.6

refractive index 

1.6000 (estimate)

Flash point:

>100°C

storage temp. 

Sealed in dry,Room Temperature

solubility 

3.6g/l

form 

Crystalline Powder

pka

pK1: 2.17 (25°C)

color 

Light yellow to beige-brown

BRN 

1877474

InChIKey

QUEKGYQTRJVEQC-UHFFFAOYSA-N

CAS DataBase Reference

2516-96-3(CAS DataBase Reference)

NIST Chemistry Reference

2-Chloro-5-nitrobenzoic acid(2516-96-3)

EPA Substance Registry System

Benzoic acid, 2-chloro-5-nitro- (2516-96-3)

Safety Information

Hazard Codes 

Xn,N,Xi

Risk Statements 

22-37/38-41-50-36/37/38

Safety Statements 

26-39-61-24/25-36

RIDADR 

UN3077 9/PG 3

WGK Germany 

1

TSCA 

Yes

HS Code 

29163900

MSDS

• Language:English Provider:2-Chloro-5-nitrobenzoic acid
• Language:English Provider:SigmaAldrich
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2-Chloro-5-nitrobenzoic acid Usage And Synthesis

Chemical Properties

light yellow to light yellow-green crystalline

Uses

2-Chloro-5-nitrobenzoic Acid is used in the synthesis of sesquiterpenoids as potential antibacterial compounds. Also used in the synthesis of substituted phenyl oxazoles as novel LSD1 inhibitors with antiproliferative activity. In addition it’s used to synthesize cathespin L inhibitors.

General Description

2-Chloro-5-nitrobenzoic acid undergoes microwave-assisted, regioselective amination reaction with aliphatic and aromatic amines to yield N-substituted 5-nitroanthranilic acid derivatives. It acts as ligand and forms a red luminescent one dimensional coordination polymer with Eu(III).

2-Chloro-5-nitrobenzoic acid(2516-96-3)Related Product Information

• 1-Chloro-3-nitrobenzene
• 4-Nitrobenzoic acid
• 2-Chloro-5-nitrophenol
• Ethyl 2-(Chlorosulfonyl)acetate
• 3-Nitrobenzoic acid
• Epichlorohydrin
• 2-Chlorobenzoic acid
• 2-Nitrochlorobenzene
• 5-Nitrosalicylic acid
• 3-Nitrosalicylic acid
• Chloroacetic acid
• NITROGEN DIOXIDE
• Difluorochloromethane
• 4-Chloronitrobenzene
• 2,4-DICHLORO-3,5-DINITROBENZOIC ACID
• 2,6-DICHLORO-3-NITROBENZOIC ACID
• 2-Chloro-3,5-dinitrobenzoic acid
• Methyl chloroformate