3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL Chemical Properties

Melting point:

210-212 °C (lit.)

Boiling point:

171.6±23.0 °C(Predicted)

Density 

1.095 (estimate)

refractive index 

1.5000 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

14.98±0.20(Predicted)

form 

solid

color 

White to Off-White

CAS DataBase Reference

2055-46-1(CAS DataBase Reference)

EPA Substance Registry System

Propylenethiourea (2055-46-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

UW5782000

HazardClass 

IRRITANT

HS Code 

29335990

MSDS

• Language:English Provider:SigmaAldrich

3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL Usage And Synthesis

Uses

Tetrahydropyrimidine-2(1H)-thione is a reactant in the preparation of aryl substituted heterocycles.

Uses

Tetrahydropyrimidine-2(1H)-thione is a reactant in the preparation of aryl substituted heterocycles.

Preparation

The preparation of 3,4,5,6-Tetrahydro-2- pyrimidinethiol is as follows:Carbon disulfide (0.2 mol) was added dropwise to a  solution of 1,3-diamino propane 1 (0.2 mol) in H2O/EtOH  (20 ml), and the temperature was remained constant at  0-5 oC. After the completion of addition, the reaction  mixture was refluxed for 12h and then cooled to room  temperature. The precipitate was collected by filtration and  recrystallized from EtOH to give pure desired compound.

3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL(2055-46-1)Related Product Information

• TERT-BUTYL TETRAHYDROPYRIMIDINE-1(2H)-CARBOXYLATE
• 2-Thiobarbituric acid
• 3,4,5,6-TETRAHYDRO-2-PYRIMIDINETHIOL
• 1,3-DIETHYL-2-THIOBARBITURIC ACID
• 1,4,5,6-TETRAHYDROPYRIMIDINE
• THIOPENTAL, [2-14C]
• 1-(4-OXO-6-HYDROXY-2-THIOXO-2,3,4,5-TETRAHYDRO-PYRIMIDO-5-YLIDEN)-5-(4,6-DIOXO-2-THIOXO-HEXAHYDRO-PYRIMIDO-5-YL)-PENTADIENE-2,4
• 5-(2-Pyridylmethylene)-2-thiobarbituric acid
• 1,3-DIPHENYL-2-THIOBARBITURIC ACID
• 2-MERCAPTODIHYDROURACIL-3-BETA-PROPIONIC ACID
• 5-ALLYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID
• (+/-)-THIOPENTAL
• MEROCYANINE 540
• 5-(4-ISOPROPYLBENZYLIDENE)-2-THIOXODIHYDROPYRIMIDINE-4,6(1H,5H)-DIONE
• AURORA 1214
• BUTTPARK 11\07-03
• 1-(3,4-DIMETHYLPHENYL)-3-PHENYL-2-THIOXODIHYDROPYRIMIDINE-4,6(1H,5H)-DIONE
• 5-(aminomethylene)-1,3-diphenyl-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione