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GLYCODEOXYCHOLIC ACID SODIUM SALT

Basic information Description Synthesis Safety Supplier Related

GLYCODEOXYCHOLIC ACID SODIUM SALT Basic information

Product Name:
GLYCODEOXYCHOLIC ACID SODIUM SALT
Synonyms:
  • GDCA
  • GDCA, SODIUM SALT
  • GLYCODEOXYCHOLIC ACID SODIUM SALT
  • 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT
  • 5BETA-CHOLAN-24-OIC ACID N-[CARBOXYMETHYL]AMIDE-3ALPHA,12ALPHA-DIOL SODIUM SALT
  • 3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-(CARBOXYMETHYL)-AMIDE SODIUM SALT
  • Glycodeoxycholic Acid, Sodiu
  • (SYNONYMS: SODIUM GLYCYLDEOXYCHOLATE)
CAS:
16409-34-0
MF:
C26H42NNaO5
MW:
471.61
EINECS:
240-455-4
Mol File:
16409-34-0.mol
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GLYCODEOXYCHOLIC ACID SODIUM SALT Chemical Properties

Melting point:
245-250 °C
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: 0.1 M at 20 °C, clear, colorless
form 
White solid
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
VMSNAUAEKXEYGP-YEUHZSMFSA-M
CAS DataBase Reference
16409-34-0
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
MB9670000
HS Code 
29221990

MSDS

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GLYCODEOXYCHOLIC ACID SODIUM SALT Usage And Synthesis

Description

Sodium deoxyglycolic acid is a kind of bile salt, and exists in bile in the form of combining with glycine or taurine to form glycodeoxycholic acid or sodium taurodeoxycholate. It is cholanoic acid that forms many organic compounds and stable molecular compounds.

Synthesis

Sodium deoxyglycolic acid is easily soluble in water and has a strong surface activity. It can be used to destroy cells to extract enzymes. Sodium deoxyglycolic acid is not directly biosynthesized by cholesterol, but is metabolized by intestinal bacteria. Synthesized from cholic acid.

Physical properties

Solid

Uses

Sodium glycodeoxycholate has been used in a study to develop more similar mimetic intestinal fluids to physiological fluids than those developed by mixed bile salt systems (MBS). It has also been used in a study to investigate Ca2+ buffering capability of bile salt micelles.

Definition

ChEBI: Sodium glycodeoxycholate is a bile acid salt that is the sodium salt of glycodeoxycholic acid. It has a role as a human metabolite. It is a bile acid salt and an organic sodium salt. It contains a glycodeoxycholate.

General Description

Sodium glycodeoxycholate is a bile salt that can be used to form biomimicking environments.

Biochem/physiol Actions

Induces apoptosis in hepatocytes; may induce DNA cleavage.

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