ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Threonine derivatives > FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH
FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH
FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH Basic information
- Product Name:
- FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH
- Synonyms:
-
- N-FMOC-O-(3,4,6,-TRI-O-ACETYL-2-ACETAMIDO-2-DEOXY-Α-D-GALACTOPYRANOSYL)-L-THREONINE
- Fmoc-L-Ser(α-D-GalNAc(Ac)3)-OH
- Fmoc-L-Thr(GalNAc(Ac)3-α-D)-OH
- Fmoc-O-β-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-L-threonine≥ 97% (HPLC)
- Fmoc-Thr(AcAcNH-α-Gal)-OH Novabiochem
- GalNAc-Thr
- 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-Fmoc threonine
- L-Threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-
- CAS:
- 116783-35-8
- MF:
- C33H38N2O13
- MW:
- 670.66
- Product Categories:
-
- Glycoamino Acid
- Carbohydrates & Derivatives
- Fluorescent Labels & Indicators
- Inhibitors
- Protein Kinase Inhibitors and Activators
- Amino Acid
- Mol File:
- 116783-35-8.mol
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FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH Chemical Properties
- Melting point:
- 178-183°C
- Boiling point:
- 857.1±65.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Acetonitrile: Soluble
Chloroform: Soluble - form
- Solid
- pka
- 3.32±0.10(Predicted)
- color
- White to off-white
- optical activity
- [α]22/D +55.0°, c = 1% in chloroform
- InChIKey
- OXLCJWGAUPPZQJ-ZNHCDWFHSA-N
- SMILES
- C1(COC(=O)N[C@H](C(=O)O)[C@@H](C)O[C@H]2O[C@@H]([C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2NC(=O)C)COC(=O)C)C2C=CC=CC=2C2C=CC=CC1=2 |&1:6,10,13,15,16,21,26,r|
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FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH Usage And Synthesis
Chemical Properties
White to off-white solid
Uses
Fluorescently labeled glycopeptides containing GalNAcα1-O-Ser/Thr residues provide valuable immunology probes for the development of cancer vaccines.
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
References
[1] KATHARINE A. WINANS. A Chemically Synthesized Version of the Insect Antibacterial Glycopeptide, Diptericin, Disrupts Bacterial Membrane Integrity†[J]. Biochemistry Biochemistry, 1999, 38 36: 11700-11710. DOI: 10.1021/bi991247f
[2] ZHI-HUA HUANG. a Totally Synthetic, Self-Assembling, Adjuvant-Free MUC1 Glycopeptide Vaccine for Cancer Therapy[J]. Journal of the American Chemical Society, 2012, 134 21: 8730-8733. DOI: 10.1021/ja211725s
FMOC-THR(GALNAC(AC)3-ALPHA-D)-OHSupplier
Jinan Samuel Pharmaceutical Co., Ltd. Gold
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- 0531-88821801 15192360884
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JIANGSU CURTIUS BIOTECH CO., LTD Gold
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- 0513-89078808 13764678260
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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Shanghai Harvest Chemical Industrial Co., Ltd.
- Tel
- 021-31038972,31038973 17321035817
- sales@harvest-chem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
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FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH(116783-35-8)Related Product Information
- Fmoc-L-Thr(α-D-Glc(Ac)4)-OH
- Fmoc-L-Asn(beta-D-Glc(Ac)4-OH
- Fmoc-L-Thr(beta-D-Gal(Ac)4)-OH
- O-(2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-N- a-(fluoren-9-yl-methoxy carbonyl)-L-serine
- Fmoc-L-Ser(α-D-Glc(Ac)4)-OH
- FMOC-L-SER(BETA-D-GALAC4)-OH
- Fmoc-L-Thr(beta-D-Glc(Ac)4)-OH
- FMOC-L-THR(ALPHA-D-MANAC4)-OH
- FMOC-SER(GALNAC(AC)3-ALPHA-D)-OH
- FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH
- N-Acetyl-D-galactosamine
- 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid
- Fmoc-L-Serine
- D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE
- METHYL 2-ACETAMIDO-2-DEOXY-A-D-GALACTOPYRANOSIDE
- FMOC-D-ALLO-THREONINOL
- 3,4,6-TRI-O-BENZYL-2-DEOXY-D-GALACTOPYRANOSE
- Oxalysine