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Posaconazole Impurity 44

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Posaconazole Impurity 44 Basic information

Product Name:
Posaconazole Impurity 44
Synonyms:
  • (5R-cis)-4-[5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofur an-3-ylmethyl]methoxy-formanilide
  • Posaconazole Formamide Impurity
  • D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-(formylamino)phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-
  • N-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)formamide
  • Posaconazole Impurity 89
  • 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-chloropentan-3-yl)-1H-1,2,4-triazol-5(4H)-one
CAS:
357189-97-0
MF:
C21H20F2N4O3
MW:
414.41
Mol File:
357189-97-0.mol
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Posaconazole Impurity 44 Chemical Properties

InChI
InChI=1/C21H20F2N4O3/c22-16-1-6-19(20(23)7-16)21(11-27-13-24-12-26-27)8-15(10-30-21)9-29-18-4-2-17(3-5-18)25-14-28/h1-7,12-15H,8-11H2,(H,25,28)/t15-,21+/s3
InChIKey
FCASVHIAWJZBAQ-CHMOWABUNA-N
SMILES
C(NC1=CC=C(OC[C@H]2C[C@@](C3=CC=C(F)C=C3F)(CN3C=NC=N3)OC2)C=C1)=O |&1:8,10,r|
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Posaconazole Impurity 44 Usage And Synthesis

Uses

(5R-cis)-4-[5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl]methoxy-formanilide is a degradation product of Posaconazole (P689600), which is an orally active triazole antifungal.

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