Secoisolariciresinol diglucoside
Secoisolariciresinol diglucoside Basic information
- Product Name:
- Secoisolariciresinol diglucoside
- Synonyms:
-
- β-D-Glucopyranoside, (2S,3S)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-
- Secoisolariciresinoldiglucoside/(SS)-Secoisolariciresinoldiglucoside
- (S,S)-SDG
- (S,S)-Secoisolariciresinol diglucoside
- CAS:
- 257930-74-8
- MF:
- C32H46O16
- MW:
- 686.7
- Mol File:
- 257930-74-8.mol
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Secoisolariciresinol diglucoside Chemical Properties
- Boiling point:
- 989.2±65.0 °C(Predicted)
- Density
- 1.52±0.1 g/cm3(Predicted)
- pka
- 9.80±0.20(Predicted)
- form
- Solid
- color
- White to off-white
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Secoisolariciresinol diglucoside Usage And Synthesis
Biological Activity
Secoisolariciresinol diglucoside ((S,S)-SDG), the major lignan in whole wheat flaxseed, has anti-inflammatory, antioxidant, anti-mutagenic, antimicrobial, anti-obesity, hypolipidemic and neuroprotective effects.
in vitro
Secoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.
in vivo
Secoisolariciresinol diglucoside (4 mg/mouse; a single po) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.
| Animal Model: < /td> | Hand feeding mice (10 weeks old, male) are injected with TNFα |
| Dosage: | 4 mg/mouse |
| Administration: | Po 2 h before ic administration of TNFα |
| Result: | Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%. |
Secoisolariciresinol diglucosideSupplier
BioBioPha Co., Ltd.
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Sichuan Wei Keqi Biological Technology Co., Ltd.
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