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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Quinoline compounds >  7,8-BENZOQUINOLINE

7,8-BENZOQUINOLINE

Basic information ?Hazardous Properties Safety Supplier Related

7,8-BENZOQUINOLINE Basic information

Product Name:
7,8-BENZOQUINOLINE
Synonyms:
  • BENZO[H]QUINOLINE
  • A-NAPHTHOQUINOLINE
  • ALPHA-NAPHTHOQUINOLINE
  • 7,8-BENZOQUINOLINE
  • 4-AZAPHENANTHRENE
  • 1-NAPHTHOQUINOLINE
  • 7,8-Benzoquinoline~alpha-Naphthoquinoline
  • 7,S-Benzochinolin
CAS:
230-27-3
MF:
C13H9N
MW:
179.22
EINECS:
205-937-0
Product Categories:
  • Thiophenes ,Thiazolines/Thiazolidines
  • API intermediates
Mol File:
230-27-3.mol
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7,8-BENZOQUINOLINE Chemical Properties

Melting point:
48-50 °C(lit.)
Boiling point:
338 °C719 mm Hg(lit.)
Density 
1.2340
refractive index 
1.7270 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
almost transparency in Methanol
pka
pK1: 4.15(+1) (20°C)
form 
Crystalline Powder
color 
Off-white to brown
BRN 
120249
CAS DataBase Reference
230-27-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzo[h]quinoline(230-27-3)
EPA Substance Registry System
Benzo[h]quinoline (230-27-3)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
RTECS 
DK1432000
HS Code 
29339900

MSDS

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7,8-BENZOQUINOLINE Usage And Synthesis

?Hazardous Properties

7,8-Benzoquinoline is combustible; burns to produce toxic fumes of nitrogen oxides.

Physical properties

7,8-Benzoquinoline is a dark yellow crystalline solid.

Uses

Benzo[h]quinoline was used to study the mutagenic activities of benzo[f]quinoline, benzo[h]quinolone and a number of their derivatives in strain TA 100 of Salmonella typhimurium. It was used in determination of nitrogen-containing polynuclear aromatic hydrocarbons in the gaseous products of the thermal degradation of polymers by HPLC- fluorescence detection. It was used as starting reagent for the synthesis of osmium and ruthenium complexes containing an N-heterocyclic carbene ligand.

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify it as for 3,4-benzoquinoline above. The picrate has m 196o(from Me2CO). [Beilstein 20 H 463, 20 III/IV 4003, 20/8 V 215.]

7,8-BENZOQUINOLINE Preparation Products And Raw materials

Raw materials

7,8-BENZOQUINOLINESupplier

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