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(-)-Corey lactone 4-phenylbenzoate alcohol

Basic information Description Safety Supplier Related

(-)-Corey lactone 4-phenylbenzoate alcohol Basic information

Product Name:
(-)-Corey lactone 4-phenylbenzoate alcohol
Synonyms:
  • (3AALPHA,4ALPHA,5BETA,6AALPHA)-(-)-HEXAHYDRO-4-(HYDROXYMETHYL)-2-OXO-2H-CYCLOPENTA[B]FURAN-5-YL 1,1'-BIPHENYL-4-CARBOXYLATE
  • (-)-COREY LACTONE 4-PHENYLBENZOATE
  • 4-Phenylbenzoyl corey lactone
  • (-)-COREY LACTONE 4-PHENYLBENZOATE ALCOHOL 99%
  • (-)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL
  • (3aR,4S,5R,6aS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzoyloxy)cyclopenta[b]furan-2-one, 99%
  • [1,1'-Biphenyl]-4-carboxylicacid,(3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-ylester
  • BPCOD
CAS:
31752-99-5
MF:
C21H20O5
MW:
352.38
EINECS:
608-667-5
Product Categories:
  • Prostaglandins
  • Latanoprost
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
31752-99-5.mol
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(-)-Corey lactone 4-phenylbenzoate alcohol Chemical Properties

Melting point:
131-132 °C(lit.)
Boiling point:
446°C (rough estimate)
alpha 
-89 º (c=1, CHCl3)
Density 
1.1818 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform, Ethyl Acetate
form 
Solid
pka
14.79±0.10(Predicted)
color 
Off-White to Pale Yellow
optical activity
[α]20/D 87°, c = 1 in chloroform
Water Solubility 
insoluble
BRN 
1294692
InChIKey
SZJVIFMPKWMGSX-UHFFFAOYSA-N
CAS DataBase Reference
31752-99-5(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29322090

MSDS

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(-)-Corey lactone 4-phenylbenzoate alcohol Usage And Synthesis

Description

(-)-Corey lactone 4-phenylbenzoate alcohol is one of the isomers of biphenyl-4-formylcorilactone, which can be used for the synthesis of prostaglandins. Prostaglandins are a class of important endogenous physiologically active substances, important mediators of various physiological processes, and have high pharmacological activity. Clinically, prostaglandins are all artificially synthesized.

Chemical Properties

Off-White to Pale Yellow Solid

Uses

(-) Corey lactone phenylbenzoate is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α.

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