RO-31-8425
RO-31-8425 Basic information
- Product Name:
- RO-31-8425
- Synonyms:
-
- RO-31-8425
- BisindolylMaleiMide X . hydrochloride [Ro 31-8425]
- 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
- Ro 31-8245
- Ro-31-8425 - CAS 131848-97-0 - Calbiochem
- RSYYBisindolylmaleimideXhydrochloride
- 1H-Pyrrole-2,5-dione, 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-
- CAS:
- 131848-97-0
- MF:
- C26H24N4O2
- MW:
- 424.49
- Product Categories:
-
- inhibitor
- Mol File:
- 131848-97-0.mol
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RO-31-8425 Chemical Properties
- Boiling point:
- 736.1±60.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- 0-6°C
- solubility
- DMSO: 10mg/mL
- form
- Red to orange-red solid
- pka
- 7.91±0.60(Predicted)
- color
- red to orange-red
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RO-31-8425 Usage And Synthesis
Uses
Bisindolylmaleimide X is a selective inhibitor of PKC, also inhibits Cdk2 and GSK-3β.
Biological Activity
Cell permeable: yes', 'Primary Target
PKC', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 15 nM for r at brain PKC; 8 nM for PKCα, 8 nM for PKCβI, 14 nM for PKCβII, 13 nM for PKCγ, and 39 nM for PKCε
RO-31-8425Supplier
TOSUN PHARM
- Tel
- 020-61855200 13326451905
- 260366801@qq.com
Jinan Ruisi Pharmaceutical Technology Co., LTD
- Tel
- 0531-69900633 18340090523
- changyuan20@163.com
Energy Chemical
- Tel
- 021-58432009 400-005-6266
- marketing1@energy-chemical.com
Aladdin Scientific
- Tel
- tp@aladdinsci.com