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6-Chloropurine riboside

Basic information Safety Supplier Related

6-Chloropurine riboside Basic information

Product Name:
6-Chloropurine riboside
Synonyms:
  • 2-(6-chloropurin-9-yl)-5-hydroxyMethyltetrahydrofuran-3,4-diol
  • 6-CLPR
  • 6-CHLORO-9-BETA-D-RIBOFURANOSYL-9H-PURINE
  • 6-CHLORO-9-(BETA-D-RIBOFURANOSYL)PURINE
  • 6-CHLOROPURINE NUCLEOSIDE
  • 6-CHLOROPURINE-9-BETA-D-RIBOFURANOSIDE
  • 6-CHLOROPURINE-9-RIBOSIDE
  • 6-CHLOROINOSINE
CAS:
5399-87-1
MF:
C10H11ClN4O4
MW:
286.67
EINECS:
226-438-4
Product Categories:
  • Bases & Related Reagents
  • Nucleotides
Mol File:
5399-87-1.mol
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6-Chloropurine riboside Chemical Properties

Melting point:
158-162 °C (dec.) (lit.)
Boiling point:
614.8±65.0 °C(Predicted)
Density 
2.03±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Sparingly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated,
pka
13.06±0.70(Predicted)
form 
Powder
color 
White to slightly yellow
Water Solubility 
Soluble in water. (10.6 mg/mL)
BRN 
40573
InChIKey
XHRJGHCQQPETRH-HMEJCUHCSA-N
CAS DataBase Reference
5399-87-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
RTECS 
UO7520800
10-23
HS Code 
29349990

MSDS

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6-Chloropurine riboside Usage And Synthesis

Chemical Properties

Colourless Crystalline Powder

Uses

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. 6-Chloropurine riboside, especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Uses

A substrate for adenosine deaminase

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