2-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Chemical Properties

Melting point:

105-109 °C(lit.)

Boiling point:

367.3±32.0 °C(Predicted)

Density 

1.11±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

form 

Crystalline Powder

pka

9.66±0.35(Predicted)

color 

White to cream

InChI

1S/C13H19BO4/c1-12(2)13(3,4)18-14(17-12)9-6-7-10(15)11(8-9)16-5/h6-8,15H,1-5H3

InChIKey

WFSJROCEOJANPD-UHFFFAOYSA-N

SMILES

COc1cc(ccc1O)B2OC(C)(C)C(C)(C)O2

CAS DataBase Reference

269410-22-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29310099

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Usage And Synthesis

Chemical Properties

white to cream crystalline powder

Uses

4-Hydroxy-3-methoxyphenylboronic acid, pinacol ester

Uses

4-Hydroxy-3-methoxyphenylboronic acid pinacol ester can be used as a reactant:

• In the Suzuki-Miyaura cross-coupling reaction.
• To prepare ethylidenedihydroindolones as potential neoplastic agents.
• To synthesize 5,6-dihydropyrrolo[2,1-b]isoquinoline derivatives, which can be utilized as scaffolds to prepare lamellarin analogs via regioselective bromination and Suzuki cross-coupling reactions.

2-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL(269410-22-2)Related Product Information

• Boric acid
• 3-Methoxyphenylboronic acid
• 4-METHOXY-2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
• 3-METHOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
• 2-[4-([1,3]DIOXOLAN-2-YLMETHOXY)-3-METHOXY-PHENYL]-4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLANE
• 1,4-BENZODIOXANE-6-BORONIC ACID, PINACOL ESTER
• 3,4-METHYLENEDIOXYPHENYLBORONIC ACID, PINACOL ESTER
• 3-BENZYLOXY-4-METHOXYBORONIC ACID, PINACOL ESTER
• 2-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL ACETATE
• 2-CHLORO-6-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL
• 3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER
• 4-(2-[2-METHOXY-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PHENOXY]-ETHYL)-MORPHOLINE
• 3-ACETOXY-4-METHOXYPHENYLBORONIC ACID, PINACOL ESTER
• 4-BENZYLOXY-3-METHOXYBORONIC ACID, PINACOL ESTER
• 2-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL