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CALANOLIDE A

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CALANOLIDE A Basic information

Product Name:
CALANOLIDE A
Synonyms:
  • CALANOLIDE A
  • (+)-(10R,11S,12S)-12-HYDROXY-6,6,10,11-TETRAMETHYL-4-PROPYL-11,12-DIHYDRO-2H,6H,10H-BENZO(1,2-B:3,4-B':5,6-B'']TRIPYRAN-2-ONE
  • CALANOLIDE A,(+)-(10R,11S,12S)-12-HYDROXY-6,6,10,11-TETRAMETHYL-4-PROPYL-11,12-DIHYDRO-2H,6H,10H-BENZO(1,2-B:3,4-B':5,6-B ]TRIPYRAN-2-ONE
  • (10R,11S,12S)-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one
  • 2H,6H,10H-Dipyrano[2,3-f:2',3'-h][1]benzopyran-2-one, 11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-propyl-, (10R,11S,12S)-
  • (+)-Calanolide A
  • (+) Calanolide A
  • NSC 675451
CAS:
142632-32-4
MF:
C22H26O5
MW:
370.44
Mol File:
142632-32-4.mol
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CALANOLIDE A Usage And Synthesis

Uses

(+)-Calanolide A is an experimental non-nucleoside reverse transcriptase inhibitor. It has potent anti-HIV activity.

Definition

ChEBI: (+)-calanolide A is an organic heterotetracyclic compound that is 11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one substituted by a hydroxy group at position 12, methyl groups at positions 6, 6, 10 and 11 and a propyl group at position 4 (the 10R,11S,12S stereoisomer). Isolated from Calophyllum lanigerum var austrocoriaceum and Calophyllum brasiliense, it exhibits potent activity against HIV-1 reverse transcriptase. It has a role as a HIV-1 reverse transcriptase inhibitor and a plant metabolite. It is an organic heterotetracyclic compound, a delta-lactone, a cyclic ether and a secondary alcohol.

CALANOLIDE ASupplier

LGM Pharma
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Shanghai Kewel Chemical Co., Ltd.
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TaiChem Taizhou Limited
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Wuhan FengyaoTonghui Chemical Products Co., Ltd.
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Twochem Co.Ltd.
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