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(R)-Baclofen

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(R)-Baclofen Basic information

Product Name:
(R)-Baclofen
Synonyms:
  • Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, (βR)-
  • D-Baclofen
  • l-Baclofen
  • 4-azanyl-3-(4-chlorophenyl)butanoic acid
  • (R)-4-Amino-3-(4-chlorophenyl)butyric acid
  • (βR)-β-(AMinoMethyl)-4-chlorobenzenepropanoic Acid
  • STX 209
  • Benzenepropanoic acid, b-(aMinoMethyl)-4-chloro-, (bR)-
CAS:
69308-37-8
MF:
C10H12ClNO2
MW:
213.66
Product Categories:
  • Inhibitors
  • Amines
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • GABA/Glycine receptor
Mol File:
69308-37-8.mol
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(R)-Baclofen Chemical Properties

Melting point:
171-174°C
Boiling point:
364.3±32.0 °C(Predicted)
Density 
1.285±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
Water Solubility 
Practically insoluble in water
solubility 
Methanol (Slightly, Sonicated), Water (Slightly, Sonicated)
form 
powder to crystaline
pka
4.04±0.10(Predicted)
color 
White to Almost white
CAS DataBase Reference
69308-37-8(CAS DataBase Reference)
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Safety Information

RIDADR 
2811
RTECS 
DA8339450
HS Code 
2922.49.2600
HazardClass 
6.1
PackingGroup 
III
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(R)-Baclofen Usage And Synthesis

Chemical Properties

White Solid

Uses

R-Enantiomer of Baclofen. Specific GABA-B receptor agonist. Muscle relaxant (skeletal).

Uses

(R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.

Definition

ChEBI: Arbaclofen is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid.

Biological Activity

More active enantiomer of ( RS )-Baclofen ((RS)-4-Amino-3-(4-chlorophenyl)butanoic acid) , a selective GABA B agonist.

storage

Room temperature

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