- Product Name:
- ISOXAFLUTOLE 45% SOLUTION
- isoxaflutole (bsi, pa iso)
- isoxaflutole (ISO) 5-cyclopropyl-1,2-oxazol-4-yl α,α,α-trifluoro-2-mesyl-p-tolyl ketone
- Isoxaflutole 0
- Mol File:
ISOXAFLUTOLE Chemical Properties
ISOXAFLUTOLE Usage And Synthesis
Isoxaflutole is a 4-benzoyl isoxazole molecule and is used as a pre- and early post-emergence herbicide for the control of a wide range of important broadleaf and grass weeds in maize (Zea mays), both in Europe and in North America. It is also registered for use in sugarcane in Central and South America (2–4). It causes characteristic bleaching of newly developed tissues of susceptible species followed by growth cessation and necrosis. Marketed as Balance for corn (maize) in the United States, and Merlin for corn in Europe; and in sugarcane, it mixes well with metolachlor, acetochlor, dimethenamid, and atrazine to complete the weed spectrum and to reduce the application rates of the latter compounds (2). Isoxaflutole also controls triazineresistant weeds in the field (4).
Isoxaflutole is readily taken up by roots and foliar
tissues and then rapidly degraded to a diketonitrile derivative
3-oxo propanenitrile) , which is translocated
throughout the plant via xylem and phloem (2,3,6,8). It
is this metabolite that inhibits HPPD (7), thereby depleting
the plastoquinone pools in developing leaves. Plastoquinone
is a cofactor in the desaturation of phytoene, levels
of which increase in bleached leaves, concomitant with
decreases in colored carotenoids (6). Although bleaching
is the primary symptom associated with HPPD inhibition,
subsequent growth suppression and necrosis are also
believed to be a consequence (8).
Isoxaflutole also degrades to the diketonitrile derivative in the soil (3,8). The half-life of isoxaflutole in soil is dependent on soil type, pH, and moisture, ranging from 12 hours to 3 days under laboratory conditions (8). The physicochemical properties of isoxaflutole and of diketonitrile play an important role in both soil and herbicidal activity and selectivity (8).
- 010-82848833- ;010-82848833-