4-tert-Butylbenzaldehyde Chemical Properties

Melting point:

245-246 °C

Boiling point:

130 °C25 mm Hg(lit.)

Density 

0.97 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.53(lit.)

Flash point:

214 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

form 

Liquid

color 

Clear colorless to yellow

explosive limit

1.3-5.6%(V)

Water Solubility 

Soluble in water.

Sensitive 

Air & Light Sensitive

BRN 

1906461

LogP

3.330 (est)

CAS DataBase Reference

939-97-9(CAS DataBase Reference)

EPA Substance Registry System

p-tert-Butylbenzaldehyde (939-97-9)

Safety Information

Hazard Codes 

Xn,N,Xi

Risk Statements 

22-43-50/53

Safety Statements 

36/37-60-61

RIDADR 

UN 3082 9/PG 3

WGK Germany 

2

F 

8-9-23

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29122990

MSDS

• Language:English Provider:4-tert-Butylbenzaldehyde
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-tert-Butylbenzaldehyde Usage And Synthesis

Uses

Used for preparing isoxazolyl penicillin derivatives. 4-tert-Butylbenzaldehyde is suitable for use in a kinetic study to evaluate the kinetic constants (KI) for inhibition of mushroom tyrosinase by 4-substituted benzaldehydes. It is also an important intermediate for the synthesis of medicines, dyes, flavor and fragrance compounds.

Uses

4-tert-Butylbenzaldehyde is suitable for use in a kinetic study to evaluate the kinetic constants (KI) for inhibition of mushroom tyrosinase by 4-substituted benzaldehydes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 37, p. 3973, 1972 DOI: 10.1021/jo00797a058
Tetrahedron Letters, 32, p. 4291, 1991 DOI: 10.1016/S0040-4039(00)92151-8

General Description

4-tert-Butylbenzaldehyde is an important intermediate for the synthesis of medicines, dyes, flavor and fragrance compounds. It is reported to be formed during the partial oxidation of 4-tert-butyltoluene by hydrogen peroxide in glacial acetic acid, catalyzed by bromide ions in combination with cobalt(II) acetate or cerium(III) acetate. Schiff base reaction between 4-tert-butylaniline and 4-tert-butylbenzaldehyde in ethanol has been carried out on-chip in the matrix assisted laser desorption ionization (MALDI) chamber, the formed imine was detected in real time.

4-tert-Butylbenzaldehyde (939-97-9)Related Product Information

• 1-Bromo-4-tert-butylbenzene
• 4-tert-Butylphenylboronic acid
• 4-tert-Butylphenylhydrazine hydrochloride
• 4-tert-Butylaniline
• 4-TERT-BUTYLPYRIDINE
• 3,5-Bis(tert-butyl)benzaldehyde
• Butylated hydroxyanisole
• 4-tert-Butylbenzenesulfonyl chloride
• 4-TERT-BUTYLBENZYL ALCOHOL
• tert-Butylhydroquinone
• Methyl 4-tert-butylbenzoate
• 4-tert-Butylcatechol
• 4-tert-Butylphenol
• BOURGEONAL
• 4-tert-Butylbenzoic acid
• DI-TERT-BUTYL ETHER
• 4-TERT-BUTYLBENZOPHENONE
• 4-tert-Butylbenzhydrazide