Nitrosobenzene Chemical Properties

Melting point:

65-69 °C (lit.)

Boiling point:

59 °C/18 mmHg (lit.)

Density 

1.1697 (rough estimate)

refractive index 

1.5389 (estimate)

storage temp. 

2-8°C

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Solid

color 

White to Brown

BRN 

605688

Stability:

Stable. Incompatible with strong oxidizing agents.

InChI

1S/C6H5NO/c8-7-6-4-2-1-3-5-6/h1-5H

InChIKey

NLRKCXQQSUWLCH-UHFFFAOYSA-N

SMILES

O=Nc1ccccc1

CAS DataBase Reference

586-96-9

NIST Chemistry Reference

Benzene, nitroso-(586-96-9)

EPA Substance Registry System

Nitrosobenzene (586-96-9)

Safety Information

Hazard Codes 

T

Risk Statements 

20/21-25

Safety Statements 

26-36/37-45

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

DA6497525

F 

9-23

TSCA 

TSCA listed

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29042000

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Oral
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation

MSDS

• Language:English Provider:Nitrosobenzene
• Language:English Provider:SigmaAldrich

Nitrosobenzene Usage And Synthesis

Chemical Properties

light yellow solid

Uses

Spin trap reagent. Has been used in the study of oxidative DNA damage and nitroso-compound-induced respiratory burst in neutrophils3,4.

Uses

Spin trap. Undergoes various addition, reduction, and oxidation reactions.

Definition

ChEBI: A nitroso compound that is the nitroso derivative of benzene; a diamagnetic hybrid of singlet O2 and azobenzene.

Purification Methods

Steam distil nitrosobenzene, then crystallise it from a small volume of EtOH with cooling below 0o, dry it over CaCl2 in a dessicator at atmospheric pressure, and store it under N2 at 0o. Alternatively it can be distilled onto a cold finger cooled with brine at ~-10o in a vacuum at 17mm (water pump), while heating in a water bath at 65-70o [Robertson & Vaughan J Chem Educ 27 605 1950]. [Beilstein 5 IV 702.]

Nitrosobenzene(586-96-9)Related Product Information

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• tert-Butyl nitrite
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