3,4,5-Trimethoxy benzoic acid Chemical Properties

Melting point:

168-171 °C (lit.)

Boiling point:

225-227 °C/10 mmHg (lit.)

Density 

1.3006 (rough estimate)

refractive index 

1.5140 (estimate)

Flash point:

225-226°C/10mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

4.23±0.10(Predicted)

form 

Liquid

color 

Clear colorless to yellow

Water Solubility 

SLIGHTLY SOLUBLE

BRN 

884655

InChIKey

SJSOFNCYXJUNBT-UHFFFAOYSA-N

LogP

1.900 (est)

CAS DataBase Reference

118-41-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzoic acid, 3,4,5-trimethoxy-(118-41-2)

EPA Substance Registry System

Benzoic acid, 3,4,5-trimethoxy- (118-41-2)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36

WGK Germany 

1

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29189090

MSDS

• Language:English Provider:Gallic acid trimethyl ether
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,4,5-Trimethoxy benzoic acid Usage And Synthesis

Description

3,4,5-Trimethoxybenzoic acid is an important fine chemical product or pharmaceutical intermediate, which is widely used in the fields of medicine, dye, food and fine chemical industry.

Synthesis

3,4,5-trimethoxybenzoic acid can be synthesised by methoxylation of gallic acid and dimethyl sulfate, and the fine product is obtained after neutralization, filtration and washing.

Physical properties

3,4,5-Trimethoxy benzoic acid is a white to beige fine crystalline powder.

Uses

A metabolite of Trimebutine (T795605).

Uses

3,4,5-Trimethoxybenzoic acid is used as intermediates in medicine and organic synthesis. It acts as a metabolite of trimebutine. It is widely used in making dyes and inks, photographic developers and used as astringents in medically.

Definition

ChEBI: A benzoic acid derivative carrying 3-, 4- and 5-methoxy substituents.

target

TNF-α

3,4,5-Trimethoxy benzoic acid(118-41-2)Related Product Information

• Gallic acid monohydrate
• Gallic acid
• 3,4,5-TRIMETHOXYBENZOIC ANHYDRIDE
• Methyl 2-nitro-3,4,5-trimethoxybenzoate
• Trimebutine
• 2-AMINO-3,4,5-TRIMETHOXYBENZOIC ACID
• 3,4,5-Trimethoxy benzoic acid
• Trimebutine maleate
• SYROSINGOPINE
• Methyl 2-amino-3,4,5-trimethoxybenzoate
• DILAZEP DIHYDROCHLORIDE
• Deserpidine
• 3,4,5-TRIETHOXYBENZOIC ACID
• Ethyl 3,4,5-trimethoxybenzoate
• Methyl 3,4,5-trimethoxybenzoate
• Reserpine
• 3,5-dimethoxy-4-phenylmethoxy-benzoate
• 8-(DIETHYLAMINO)OCTYL 3,4,5-TRIMETHOXYBENZOATE HYDROCHLORIDE