N,N-Dimethyloctylamine Chemical Properties

Melting point:

-57 °C (lit.)

Boiling point:

195 °C (lit.)

Density 

0.765 g/mL at 25 °C (lit.)

vapor density 

5.4 (vs air)

vapor pressure 

0.8 mm Hg ( 25 °C)

refractive index 

n20/D 1.424(lit.)

Flash point:

149 °F

storage temp. 

Store below +30°C.

form 

Liquid

pka

9.86±0.28(Predicted)

color 

Clear

Water Solubility 

slightly soluble

Sensitive 

Air Sensitive

BRN 

1698081

LogP

2.17 at 21℃

CAS DataBase Reference

7378-99-6(CAS DataBase Reference)

NIST Chemistry Reference

N,N-Dimethyloctylamine(7378-99-6)

EPA Substance Registry System

N,N-Dimethyloctylamine (7378-99-6)

Safety Information

Hazard Codes 

T,C

Risk Statements 

25-37/38-41-34-36/37

Safety Statements 

26-39-45-36/37/39-27

RIDADR 

UN 2922 8/PG 3

WGK Germany 

3

RTECS 

RG8075000

F 

10-23

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29211980

Toxicity

LD50 orally in Rabbit: 162 mg/kg

MSDS

• Language:English Provider:N,N-Dimethyloctylamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N,N-Dimethyloctylamine Usage And Synthesis

Chemical Properties

Liquid

Uses

Barlene(R) 8S is a tertiary amine used typically as an intermediate in the manufacture of quaternary ammonium compounds.

Uses

N,N-Dimethyl-n-octylamine is used as ion-pairing agent in the quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC. It acts as a counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography. Further, it is used in the study of chiral separations by complexation with proteins in capillary zone electrophoresis. In addition to this, it is used as a mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 3073, 1950 DOI: 10.1021/ja01163a074
Tetrahedron Letters, 18, p. 1937, 1977

N,N-Dimethyloctylamine(7378-99-6)Related Product Information

• STRYCHNINE
• RESCINNAMINE
• Tetradecyltrimethylammonium bromide
• TRIDODECYLAMINE
• Domiphen bromide
• Benzyldodecyldimethylammonium bromide
• Benzyldimethylhexadecylammonium chloride
• Reserpine
• LDAO
• N,N-Dimethyldodecylamine
• 10,11-Dimethoxystrychnine
• N,N-Diethyldodecanamide
• Yohimbine
• N-Methyldioctylamine
• N,N-Dimethyloctylamine
• 4,4'-Trimethylenebis(1-methylpiperidine)
• Tri-n-octylamine
• trichloro(N,N-dimethyloctylamine)boron