N-Methylparoxetine Chemical Properties

Melting point:

109.0 to 113.0 °C

Boiling point:

443.7±45.0 °C(Predicted)

Density 

1.198±0.06 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

8.48±0.20(Predicted)

color 

Off-White to Pale Yellow

BRN 

7468178

InChI

InChI=1S/C20H22FNO3/c1-22-9-8-18(14-2-4-16(21)5-3-14)15(11-22)12-23-17-6-7-19-20(10-17)25-13-24-19/h2-7,10,15,18H,8-9,11-13H2,1H3/t15-,18-/m0/s1

InChIKey

MOJZPKOBKCXNKG-YJBOKZPZSA-N

SMILES

N1(C)CC[C@@H](C2=CC=C(F)C=C2)[C@H](COC2=CC=C3OCOC3=C2)C1

CAS DataBase Reference

110429-36-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

T,N

Risk Statements 

25-50/53

Safety Statements 

45-60-61

RIDADR 

UN 2811 6.1 / PGIII

HS Code 

2933.39.9200

N-Methylparoxetine Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A drug impurity of Paroxetin, a selective serotonin reuptake inhibitor. Paroxetine USP Related Compound F.

Definition

ChEBI: N-methylparoxetine is a member of the class of benzodioxoles that is paroxetine in which the piperidine hydrogen is substituted by a methyl group. It is a drug impurity of the antidepressant, paroxetine. It has a role as an apoptosis inducer, a serotonin uptake inhibitor and an impurity. It is a member of benzodioxoles, an aromatic ether, a member of piperidines, a tertiary amino compound and a member of monofluorobenzenes. It is functionally related to a paroxetine.

N-Methylparoxetine(110429-36-2)Related Product Information

• Diphenyldimethoxysilane
• Triacetonediamine
• Tribenuron methyl
• Haloperidol
• Methyl salicylate
• DROPERIDOL
• Paroxetine
• 4-Methoxyphenylacetone
• 2,2,6,6-Tetramethyl-4-piperidinol
• Methylhexahydrophthalic anhydride
• 4,4'-Diphenylmethane diisocyanate
• Methylene Blue
• Thiophanate-methyl
• Paroxetine hydrochloride
• Methyl
• Methylene Chloride
• Methyl bromide
• 4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine