N-Cbz-L-Leucine Chemical Properties

alpha 

-17 º (c=2, ethanol)

Boiling point:

408.52°C (rough estimate)

Density 

1 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.512(lit.)

Flash point:

85 °F

storage temp. 

Sealed in dry,2-8°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

pka

4.00±0.21(Predicted)

form 

viscous liquid

Specific Gravity

1.0

color 

Colorless to Light yellow

optical activity

[α]20/D 17°, c = 2 in ethanol

Water Solubility 

Not miscible or difficult to mix in water. Soluble in chloroform, DMSO and methanol.

BRN 

1253861

CAS DataBase Reference

2018-66-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

10-20/22-37/38-40-41-36/37/38-20/21/22-67-63-19

Safety Statements 

16-26-36/37/39-45-36-36/37-60

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

RTECS 

OH2921000

HS Code 

29242990

MSDS

• Language:English Provider:Z-Leu-OH
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N-Cbz-L-Leucine Usage And Synthesis

Chemical Properties

yellow oil or weak solid

Uses

Reactant for:

• Peptide-based preparation of potential antitumor agents
• Preparation of cyclopropyl peptidomimetics
• Peptide synthesis

Definition

ChEBI: A L-leucine derivative obtained by the substitution of a benzyloxycarbonyl group on the nitrogen atom.

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