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ETHYL PHENYLPHOSPHINATE

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ETHYL PHENYLPHOSPHINATE Basic information

Product Name:
ETHYL PHENYLPHOSPHINATE
Synonyms:
  • ETHYL PHENYLPHOSPHINATE
  • Ethoxyphenylphosphine oxide
  • Phenylphosphinic acid ethyl
  • Ethyl phenyl phosphoinate
  • Phenyl ethylphosphinate
  • O-Ethylphenylphosphinate
  • phenylphosphinicacidethylester
  • Phenyl-phosphinicacidethylester
CAS:
2511-09-3
MF:
C8H11O2P
MW:
170.15
Product Categories:
  • Organic Building Blocks
  • Phosphonates/Phosphinates
  • Phosphorus Compounds
  • Aromatic Building Blocks
Mol File:
2511-09-3.mol
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ETHYL PHENYLPHOSPHINATE Chemical Properties

Boiling point:
94-95 °C1 mm Hg(lit.)
Density 
1.129 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.526(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
SZ5600000

MSDS

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ETHYL PHENYLPHOSPHINATE Usage And Synthesis

Uses

Ethyl phenylphosphinate may be used in the preparation of the following diethyl imidazol-2-yl-(amino) methylphosphonates and phosphinates:

  • imidazol-2-yl-methyl(N-butylamino)phosphonate diethyl ester
  • imidazol-2-yl-methyl(N-benzylamino)phosphonate diethyl ester
  • imidazol-2-yl-methyl(N-butylamino)phenylphosphinate ethyl ester
  • imidazol-2-yl-methyl(N-benzylamino)phenylphosphinate ethyl ester

General Description

Ethyl phenylphosphinate is an organophosphorous compound. It undergoes regioselective Markovnikov addition reaction with terminal alkynes in the presence of palladium-1,2-bis(diphenylphosphino)ethane complex (catalyst). Ethyl phenylphosphinate is the photodecomposition product of Inezin (S-benzyl O-ethyl phenylphosphonothiolate) on the ultraviolet irradiation. It can be prepared by the reaction of phosphinic acid with ethyl chloroformate in the presence of pyridine. Its ethylation using ethyl trimethylsilyl phenylphosphonite or the corresponding trimethylstannyl ester has been described. Its free-radical addition to ethylene has been reported to proceed with the retention of configuration.

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