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Tocopheryl acetate

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Tocopheryl acetate Basic information

Product Name:
Tocopheryl acetate
Synonyms:
  • 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
  • [2r-[2r*(4r*,8r*)]]-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-ol acetate
  • Tocopherolacetat-alpha (high mass adjustment=50%)
  • Tocopherolcetat-alpha (high mass adjustment=100%)
  • 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanoacetate
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
  • 2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,acetate
  • O-ACETYL-ALPHA-TOCOPHEROL
CAS:
7695-91-2
MF:
C31H52O3
MW:
472.74
EINECS:
231-710-0
Product Categories:
  • food additives
  • Vitamin series
  • Organics
  • Antioxidant
  • Biochemistry
  • Vitamins
  • Vitamins and derivatives
Mol File:
7695-91-2.mol
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Tocopheryl acetate Chemical Properties

Melting point:
-28°C
Boiling point:
224 °C0.3 mm Hg(lit.)
Density 
0.96 g/mL at 20 °C (lit.)
vapor density 
16.3 (vs air)
refractive index 
n20/D 1.497
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils.
form 
neat
color 
Clear yellow viscous liquid
Specific Gravity
0.962 (20/4℃)
Odor
Odorless
Water Solubility 
Immiscible with water.
Sensitive 
Air & Light Sensitive
Merck 
14,9495
BRN 
97512
InChIKey
ZAKOWWREFLAJOT-CEFNRUSXSA-N
CAS DataBase Reference
7695-91-2(CAS DataBase Reference)
NIST Chemistry Reference
(+)-«ALPHA»-tocopherol acetate(7695-91-2)
EPA Substance Registry System
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate (7695-91-2)
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Safety Information

Safety Statements 
24/25
WGK Germany 
1
RTECS 
GA8747000
8-10-23
TSCA 
Yes
HS Code 
29362800

MSDS

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Tocopheryl acetate Usage And Synthesis

Chemical Properties

Light yellow to yellow clear liquid

Uses

anti-Altzheimer therapeutic

Uses

vitamin E acetate (tocopherol acetate) is an anti-oxidant with skinmoisturizing activity. given its free-radical scavenging properties, it is useful in uV protective products. Vitamin e acetate is commonly used to replace vitamin e because it is more stable and is converted to vitamin e by the body.

Uses

Vitamin E (α-tocopherol) occurs naturally in most vegetable oils. The highest concentrations are found in com, soybean oils, sunflower seed, wheat germ, rapeseed, alfalfa, and lettuce. It is claimed to have age-retardant properties. May produce erythemamultiforme-like eruptions. It is used in a number of cosmetic products; creams are used for scars, striae, and bums; in pharmaeeutical ereams and deodorants; as an antioxidant in foods.

Hazard

A reproductive hazard.

Contact allergens

Tocopherol and tocopheryl acetate are used mainly as antioxidants. Tocopheryl acetate, an ester of tocopherol (vitamin E), can induce allergic contact dermatitis.

Purification Methods

It is a viscous liquid which is purified by distillation under high vacuum under N2 or Ar and stored in sealed ampoules in the dark. It is considerably more stable to light and air than the parent unacetylated vitamin. It is insoluble in H2O but freely soluble in organic solvents. All eight stereoisomers have been synthesised. The commercially pure d-tocopheryl acetate (2R,4'R,8'R) has b 180-200o/0.7mm and [] D 20 +3.9o (c 5, EtOH); see above. [Cohen et al. Helv Chim Acta 64 1158 1981, Beilstein 17/4 V 169.]

Tocopheryl acetateSupplier

Wuhan Jingxiu Research Biological Co., Ltd. Gold
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