2-((3,5-DIMETHYL-4-HYDROXYPHENYL)-METHYLENE)-4-CYCLOPENTENE-1,3-DIONE Chemical Properties

Boiling point:

436.2±44.0 °C(Predicted)

Density 

1.313±0.06 g/cm3(Predicted)

storage temp. 

+2C to +8C

solubility 

DMF: slightly; DMSO: 0.33 mg/ml; Ethanol: slightly

form 

Light orange solid

pka

9.47±0.40(Predicted)

color 

light orange

InChI

1S/C14H12O3/c1-8-5-10(6-9(2)14(8)17)7-11-12(15)3-4-13(11)16/h3-7,17H,1-2H3

InChIKey

YHWRISYBKMXSGJ-UHFFFAOYSA-N

SMILES

Oc1c(cc(cc1C)C=C2C(=O)C=CC2=O)C

Safety Information

WGK Germany 

WGK 1

Storage Class

11 - Combustible Solids

2-((3,5-DIMETHYL-4-HYDROXYPHENYL)-METHYLENE)-4-CYCLOPENTENE-1,3-DIONE Usage And Synthesis

Uses

TX-1918 is a potent inhibitor for eEF2K.

Biological Activity

Cell permeable: yes', 'Primary Target
eEF2-K', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 440 nM against eEF2-K

2-((3,5-DIMETHYL-4-HYDROXYPHENYL)-METHYLENE)-4-CYCLOPENTENE-1,3-DIONE(503473-32-3)Related Product Information

• 4-CYCLOPENTENE-1,3-DIONE