3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID Chemical Properties

Melting point:

185℃ (ethyl acetate tetrahydrofuran )

Boiling point:

562.8±45.0 °C(Predicted)

Density 

1.13±0.1 g/cm3 (20 ºC 760 Torr)

storage temp. 

Sealed in dry,2-8°C

solubility 

Chloroform (Slightly)

form 

Solid

pka

3.94±0.10(Predicted)

color 

White to Off-White

3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID Usage And Synthesis

Chemical Properties

White solid

Uses

3-(N-1-Trityl-imidazol-4-yl)propionic Acid is an intermediate used to prepare imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase. It is also used in the synthesis of nonracemic arylpiperazinone analogs of the carboxyl-terminal CAAL sequence of protein geranylgeranyltransferase-I (PGGTase-I) as selective inhibitors of PGGTase-I and of protein farnesyltransferase.

3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID(160446-35-5)Related Product Information

• Boc-His(Trt)-OH
• N-Fmoc-N'-trityl-D-histidine
• FMOC-D-HIS(MTT)-OH
• N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester
• H-His(Trt)-OH
• 3,5-DIIODO-D-TYROSINE HYDROCHLORIDE
• Fmoc-His(Trt)-OH
• H-HIS(1-TRT)-OTBU
• TRT-HIS(TRT)-OH
• N-α-Fmoc-N-im-trityl-L-histidine N-carboxyanhydride
• AC-HIS(1-TRT)-OH
• 3-(N-1-TRITYL-IMIDAZOL-4-YL)PROPIONIC ACID
• D-HISTIDINE(1-TRT)-OME HCL
• N-im-Trityl-D-histidine
• FMOC-HIS(MTT)-OH
• FMOC-HIS(MMT)-OH
• H-His(Trt)-OMe · HCl
• ALOC-HIS(TRT)-OH