Chlorodimethylphenylsilane Chemical Properties

Melting point:

<0°C

Boiling point:

194-198 °C

Density 

1.017 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.509(lit.)

Flash point:

143 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Miscible with tetrahydrofuran, ether and hexane.

form 

clear liquid

color 

Colorless to Light yellow

Specific Gravity

1.017

Water Solubility 

MAY DECOMPOSE

Hydrolytic Sensitivity

8: reacts rapidly with moisture, water, protic solvents

Sensitive 

Moisture Sensitive

BRN 

606292

InChIKey

KWYZNESIGBQHJK-UHFFFAOYSA-N

CAS DataBase Reference

768-33-2(CAS DataBase Reference)

NIST Chemistry Reference

Silane, chlorodimethylphenyl-(768-33-2)

EPA Substance Registry System

Silane, chlorodimethylphenyl- (768-33-2)

Safety Information

Hazard Codes 

C

Risk Statements 

34-37

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2987 8/PG 2

WGK Germany 

1

F 

10-21

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Chlorodimethylphenylsilane Usage And Synthesis

Chemical Properties

clear colorless to light yellow liquid

Uses

Chlorodimethylphenylsilane is used in the synthesis of enantioenriched allenylsilanes through an ortho-ester Claisen rearrangement of chiral and silylpropargylic alcohols.

Application

Chlorodimethylphenylsilane can be used for nucleophilic silylation; alcohol derivatization; antenna chromophores; enolate capture; and Kumada-FlemingTamao oxidation.

Hazard

Chlorodimethylphenylsilane is a combustible liquid, it can causes severe skin burns and eye damage.

storage

Like other chlorosilanes, this compound can be destructive to tissue of the  mucous membranes, upper respiratory tract, eyes and skin. Store in a cool dry place; the compound is moisture  sensitive.

Purification Methods

Fractionate it through a 1.5 x 18inch column packed with stainless steel helices, or a spinning band column. [Daudt & Hyde J Am Chem Soc 74 386 1952, Lewis et al. J Am Chem Soc 70 1115 1948, Eaborn J Chem Soc 494 1953.] It is used for standardising MeLi or MeMgBr which form Me3PhSi which is estimated by GC. [Maienthal et al. J Am Chem Soc 76 6392 1954, House & Respess J Organomet Chem 4 95 1965, Beilstein 16 IV 1475.] TOXIC and MOISTURE SENSITIVE.

Chlorodimethylphenylsilane(768-33-2)Related Product Information

• DIMETHYLSILANE
• Dimethyldimethoxysilane
• tert-Butyldimethylsilyl chloride
• Diethoxydimethylsilane
• PHENYLACETOXYTRIMETHYLSILANE
• Phenyltris(trimethylsiloxy)silane
• Trimethoxyphenylsilane
• Chloro(chloromethyl)dimethylsilane
• DIMETHYLTHEXYLSILYL CHLORIDE
• PHENYLDICHLOROSILANE
• Chloromethyl silane
• Phenyltrichlorosilane
• Phenyltriethoxysilane
• CHLORODIMETHYLVINYLSILANE
• Dichlorodiphenylsilane
• CHLOROPHENYLSILANE
• 3,5-Bis(trifluoromethyl)phenyldimethylchlorosilane
• Chlorodimethylpentafluorophenylsilane