diSulfo-Cy5 alkyne Chemical Properties

solubility 

Soluble in Water, DMSO, DMF, DCM

Appearance

Dark blue solid

ex/em

649/672 nm (PBS buffer)

ε(extinction coefficient)

271000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.28

InChIKey

XKVHPAQUKWEXLO-UHFFFAOYSA-N

SMILES

C(N1C(C(C)(C)C2=CC(S(O)(=O)=O)=CC=C12)=CC=CC=CC1=[N+](C2=CC=C(S([O-])(=O)=O)C=C2C1(C)C)C)CCCCC(=O)NCC#C.[NaH]

diSulfo-Cy5 alkyne Usage And Synthesis

Description

Sulfo-Cy5 alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach the deeply colored and photostable Cyanine5 fluorophore to various azide-bearing molecules. Sulfo-Cyanine5 is a sulfonated dye with high hydrophilicity and aqueous solubility, high extinction coefficient, good quantum yield, and compatibility with many instruments. This reagent is recommended for conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

Chemical Properties

Appearance: Dark blue solid
ex/em: 649/672 nm (PBS buffer)
Extinction coefficient (ε): 271000 L??mol??1??cm??1
Quantum yield (Φ): 0.28

Uses

DiSulfo-Cy5 alkyne is a fluorescent dye can be used as a click chemistry reagent[1].

References

[1] Majouga AG, Dontsova OA, et al. Mixed valence copper(I,II) binuclear complexes with unexpected structure: synthesis, biological properties and anticancer activity. J Med Chem. 2014 Jul 24;57(14):6252-8. DOI:10.1021/jm500154f

diSulfo-Cy5 alkyne(1617497-19-4)Related Product Information

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• Cy5.5 alkyne
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• Sulfo-Cy7 alkyne
• 15-hexadecynoic acid
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• diSulfo-Cyanine5 Me-tetrazine