FMOC-L-PROPARGYLGLYCINE Chemical Properties

Melting point:

175 °C

Boiling point:

472°C (rough estimate)

Density 

1.2712 (rough estimate)

refractive index 

1.5600 (estimate)

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Sparingly)

form 

Solid

pka

3.42±0.10(Predicted)

color 

White to Off-White

optical activity

8.4416°(C=1.0081g/100ml MEOH)

InChI

InChI=1S/C20H17NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h1,3-6,8-11,17-18H,7,12H2,(H,21,24)(H,22,23)/t18-/m0/s1

InChIKey

DJGMNCKHNMRKFM-SFHVURJKSA-N

SMILES

C(O)(=O)[C@@H](NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)CC#C

CAS DataBase Reference

198561-07-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Safety Statements 

24/25-25-24

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29242990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

FMOC-L-PROPARGYLGLYCINE Usage And Synthesis

Chemical Properties

white powder

Uses

Fmoc-propargyl-Gly-OH is an Fmoc protected glycine derivative useful for solid phase peptide synthesis techniques. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function. N-Fmoc-L-propargylglycine is a non-natural amino acids used for the triazole cross-link.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

FMOC-L-PROPARGYLGLYCINE(198561-07-8)Related Product Information

• (S)-2-AMINOHEX-5-YNOIC ACID
• BOC-D-ALLYLGLYCINE DCHA SALT
• FMOC-L-PIPECOLIC ACID
• BOC-(S)-3-AMINO-5-HEXENOIC ACID
• (3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-[tri(phenyl)methylamino]pentanoic acid
• (S)-2-(TERT-BUTOXYCARBONYLAMINO)HEX-5-YNOIC ACID
• FMOC-L-PENTAFLUOROPHENYLALANINE
• FMOC-L-STYRYLALANINE
• FMOC-PEN(ACM)-OH
• Fmoc-L-Penicillamine
• Boc-β-homoasparagine
• Boc-β-homoglutamine
• H-β-homoglutamine·HCl
• Fmoc-β-homoglutamine(Trt)
• 4-PENTYNOIC ACID
• L-Propargylglycine
• 4-Fluorocinnamic acid
• L-Propargylglycine HCL