Secalciferol
Secalciferol Basic information
- Product Name:
- Secalciferol
- Synonyms:
-
- Stilbitol
- (24r)-hydroxycalcidiol
- (3-beta,5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-3,24,25-triol
- ANTI-VEGFR2 (FLK1/KDR)(C-TERMINAL) antibody produced in rabbit
- Secalciferol/ 24R, 25-Dihydroxycholecalciferol
- Secalciferol, 24R,25-dihydroxycholecalciferol, 24R,25-dihydroxyvitamin D3, 24R 25 DHCC
- 24(r),25-dihydroxycholecalciferol
- 7,10(19)-triene-3,24,25-triol,(3-beta,5z,7e,24r)-10-secocholesta-5
- CAS:
- 55721-11-4
- MF:
- C27H44O3
- MW:
- 416.64
- Product Categories:
-
- Chiral Reagents
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Pharmaceuticals
- Other APIs
- APIs
- Mol File:
- 55721-11-4.mol
Secalciferol Chemical Properties
- Melting point:
- 63-65°C
- Boiling point:
- 474.91°C (rough estimate)
- Density
- 1.0362 (rough estimate)
- refractive index
- 1.4700 (estimate)
- storage temp.
- Amber Vial, -20°C Freezer, Under Inert Atmosphere
- solubility
- Soluble in DMSO
- form
- Powder
- pka
- 14.67±0.29(Predicted)
- color
- White to off-white
- biological source
- synthetic
- BRN
- 4567039
- Stability:
- Light Sensitive, Temperature Sensitive
- InChIKey
- FCKJYANJHNLEEP-AOWQBJNISA-N
Safety Information
- Hazard Codes
- T+
- Risk Statements
- 28
- Safety Statements
- 28-36/37-45
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- VS2895000
Secalciferol Usage And Synthesis
Chemical Properties
White Solid
Uses
A labelled metabolite of Vitamin D, a possibly anti-inflammatory steroid.
Uses
A metabolite of Vitamin D, a possibly anti-inflammatory steroid.
Uses
A labelled metabolite of Vitamin D, a possible anti-inflammatory steroid.
Definition
ChEBI: (24R)-24,25-dihydroxycalciol is a seco-cholestane, a hydroxy seco-steroid and a hydroxycalciol. It has a role as a human metabolite.
brand name
Osteo D (Teva, Israel).
Biological Activity
(24R)-24,25-Dihydroxyvitamin D3 plays an essential role in calcium and phosphorus homeostasis. (24R)-24,25-Dihydroxyvitamin D3 along with 1α,25(OH)2D3 stimulates bone metabolism.', 'Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog th at is metabolized to 1,25-dihydroxycholecalciferol, the biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 24R,25-Dihydroxyvitamin D3 is a catabolite of 25-Dihydroxyvitamin D3 and a putative regulator of developmental bone formation. 24R,25-Dihydroxyvitamin D3 is a substrate for renal 25-hydroxyvitamin D3 1 α-hydroxylase. 24R,25-Dihydroxyvitamin D3 is an endogenous regulator of apo A-I synthesis through a VDR-independent signaling mechanism and an inhibitor of Pi-induced apoptosis through Ca2+, PLD, and PLC signaling and through LPA-LPA1/3-G(αi)-PI(3)K-mdm2-mediated p53 degradation.
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