1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl-, chloride (1:1) Chemical Properties

solubility 

Soluble in organic solvents such as DMF

form 

Solid

color 

Purple to purplish red

Appearance

Dark blue solid

ex/em

680/698 nm (EtOH/PBS buffer)

ε(extinction coefficient)

198000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.20

InChIKey

SWLMDNMICOSZPR-UHFFFAOYSA-M

SMILES

CC1(C(=[N+](CCCCCC(=O)ON2C(CCC2=O)=O)C2C=CC3=CC=CC=C3C1=2)C=CC=CC=C1N(C2C=CC3=CC=CC=C3C=2C1(C)C)C)C.[Cl-]

1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl-, chloride (1:1) Usage And Synthesis

Chemical Properties

Appearance: Dark blue solid
ex/em: 680/698 nm (EtOH/PBS buffer)
Extinction coefficient (ε): 198000 L??mol??1??cm??1
Quantum yield (Φ): 0.20

Uses

Cyanine5.5 NHS ester chloride is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds[1].

References

[1] Zhu S, et al. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. J Drug Target. 2015 Apr;23(3):257-65. DOI:10.3109/1061186X.2014.988217

1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl-, chloride (1:1)(1469277-96-0)Related Product Information

• Cy5.5
• Cy7
• Cy3
• Cy5
• Cyanine5 NHS ester
• Cy5
• Cyanine3.5 NHS ester
• Sulfo Cyanine3 NHS ester