Domperidone Impurity 15 Chemical Properties

Melting point:

66°C

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), Water (Slightly, Heated, Sonicated)

form 

Solid

color 

White to Off-White

Domperidone Impurity 15 Usage And Synthesis

Uses

1,3-Bis(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one (~90%) is an intermediate in the synthesis of 3’-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]propyl Domperidine (Domperidine Impurity F) (C365315), an impurity of the gastrokinetic and antinauseant drug Domperidone (D531100(P)), which is a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.

Domperidone Impurity 15(142799-22-2)Related Product Information

• Domperidone maleate
• Domperidone
• Domperidone Impurity 13
• 2-Methylbenzimidazole
• DoMperidoneiMpurityE
• DoMperidone
• ethyl 4-[(2-nitrophenyl)amino]piperidine-1-carboxylate
• ethyl 4-[(4-chloro-2-nitrophenyl)amino]piperidine-1-carboxylate
• 2H-Benzimidazol-2-one, 1,1'-(1,3-propanediyl)bis[1,3-dihydro-
• DoMperidone EP IMpurity D
• ethyl 4-[(2-amino-4-chlorophenyl)amino]piperidine-1-carboxylate
• 1-(2-PROPENYL)-2-BENZIMIDAZOLIDINONE
• 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
• 5-Chloro-1-(4-piperidyl)-2-benzimidazolinone
• 1-PIPERIDINECARBOXYLIC ACID, 4-[(4-AMINO-5-CHLOROPHENYL)AMINO], ETHYL ESTER
• 1-(3-BroMopropyl)-1,3-dihydro-2H-benziMidazol-2-one
• 1-(3-chloropropyl)-1,3-dihydro-3-(1-methylvinyl)-2H-benzimidazol-2-one
• DoMperidone-d6